Evidence map›Paper›PMID 40804225›Full record

SynthesisObesity surgery2025

Comparative Effect of Roux-en-Y Gastric Bypass vs. One-Anastomosis Gastric Bypass for Revisional Surgery After Sleeve Gastrectomy With Insufficient Clinical Response: A Systematic Review and Meta-analysis.

Wilson Silva-Chavez, Alexander Bustamante-Cabrejo, Jose Caballero-Alvarado, Víctor Lau-Torres, Joaquín Sarmiento-Falen, Carlos Zavaleta-Corvera

Erratum issuedAbstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Wilson Silva-ChavezAntenor Orrego Private University, Trujillo, Peru.
Alexander Bustamante-CabrejoAntenor Orrego Private University, Trujillo, Peru.
Jose Caballero-AlvaradoAntenor Orrego Private University, Trujillo, Peru.
Víctor Lau-TorresNational University of Trujillo, Trujillo, Peru.
Joaquín Sarmiento-FalenAntenor Orrego Private University, Trujillo, Peru.
Carlos Zavaleta-CorveraUniversidad Cientifica del Sur, Lima, Peru. czavaletac3@upao.edu.pe.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSleeve gastrectomy (SG) is the most performed bariatric procedure worldwide. Although effective in the short term, it has a high insufficient clinical response rate, leading to weight regain and gastroesophageal reflux disease (GERD), necessitating revisional surgery. The two primary options for conversion procedures are the Roux-en-Y gastric bypass (RYGB), considered the gold standard, and the one-anastomosis gastric bypass (OAGB), recognized for its simplicity and metabolic benefits.

objectiveTo compare the effectiveness and safety of RYGB and OAGB as revisional procedures after insufficient clinical response to SG in terms of weight loss, metabolic improvements, surgical complications, and operative time.

methodsThis systematic review and meta-analysis followed PRISMA guidelines. A comprehensive search was conducted across six databases (PubMed, Scopus, Web of Science, Cochrane, Ovid/Medline, and Embase). Out of 236 identified studies, five met the inclusion criteria. Data were analyzed using relative risk (RR) for categorical variables and mean difference (MD) for continuous outcomes, applying a random-effects model.

resultsOAGB showed a statistically significant advantage in total weight loss percentage (TWL%) compared to RYGB (MD, - 1.24; 95% CI, - 1.94, - 0.53; p = 0.0006). However, no significant difference was observed in BMI reduction (MD, 0.00; 95% CI, - 1.24, 1.24; p = 1.00). Both techniques demonstrated similar remission rates for hypertension (RR, 0.85; 95% CI, 0.60-1.22; p = 0.38), GERD (RR, 1.00; 95% CI, 0.86-1.17; p = 0.97), and type 2 diabetes (RR, 0.97; 95% CI, 0.79-1.21; p = 0.81). Postoperative complications were comparable between groups (RR, 0.89; 95% CI, 0.67-1.18; p = 0.42). However, operative time was significantly shorter in OAGB (MD, 30.10 min; 95% CI, 27.89, 32.32; p < 0.00001).

conclusionOAGB demonstrated greater total weight loss and a shorter operative time compared to RYGB, with a comparable safety profile. Both techniques were equally effective in managing hypertension and GERD, though OAGB showed a non-significant trend favoring type 2 diabetes remission. RYGB may be preferable for patients with severe GERD. Further high-quality, long-term studies are needed to establish the optimal revisional procedure for SG.

Indexed as

GastrectomyGastric BypassObesity, MorbidReoperationGastroesophageal RefluxHumansOperative TimePostoperative ComplicationsTreatment OutcomeWeight LossFailed sleeve gastrectomyOne-anastomosis gastric bypassRevisional bariatric surgeryRoux-en-Y gastric bypassWeight loss surgery

Identifiers

PMID40804225

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.