Evidence map›Paper›PMID 40804351›Full record

ArticleScientific reports2025

Surface-tailored graphene nanosheets targeting PI3K/Akt signaling of breast cancer cells.

Sabapathi Durgadevi, Ponnuchamy Kumar

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sabapathi DurgadeviFood Chemistry and Molecular Cancer Biology, Department of Animal Health and Management, Alagappa University, 630 003, Karaikudi, Tamil Nadu, India.
Ponnuchamy KumarFood Chemistry and Molecular Cancer Biology, Department of Animal Health and Management, Alagappa University, 630 003, Karaikudi, Tamil Nadu, India. kumarp@alagappauniversity.ac.in.

Funding

RUSA 2.0 F.24-51/2014-U, Policy (TN Multi-Gen), Department of Education, Government of India
6 · The paper itself

Abstract

Herein, we report graphene nanosheets fabricated using liquid-phase exfoliation of graphite employing cetyltrimethylammonium chloride (CTAC) in an aqueous medium. The salient features of CTAC-assisted graphene nanosheets are as follows: (i) the concentration of graphene dispersed in water is found to be 26.01 mg/mL at 50 mg with a Critical Micelle Concentration (CMC) Value of 3 mg/mL (9.375 mM); (ii) rapid exfoliation is assisted by CTAC via sonication, which develops hydrophilic micelles on graphitic surface; (iii) the strong repulsive force of CTAC prevents re-aggregation of graphene sheets by means of electrostatic interaction as revealed by zeta potential measurement (+ 33.8 mV); (iv) the graphene nanosheets display excellent anticancer properties against MCF-7 (IC

Indexed as

Breast NeoplasmsGraphiteNanostructuresPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionAntineoplastic AgentsApoptosisCell Line, TumorCetrimoniumFemaleHumansMCF-7 CellsSurface PropertiesAntineoplastic AgentsCetrimoniumGraphitePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktApoptosisBreast cancerCTACGrapheneLiquid-phase exfoliationPI3K/Akt signaling

Identifiers

PMID40804351
PMCPMC12350778

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.