Evidence map›Paper›PMID 40804647›Full record

ReviewDiabetology & metabolic syndrome2025

Comparative effectiveness of high-intensity interval training and moderate-intensity continuous training on cardiometabolic health in patients with diabesity: a systematic review and meta-analysis of randomized controlled trials.

Sameer Badri Al-Mhanna, Eric Tsz-Chun Poon, Barry A Franklin, Mark A Tarnopolsky, John A Hawley, John M Jakicic, Emmanuel Stamatakis, Jonathan P Little, Linda S Pescatello, Deborah Riebe and 9 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Diabetology & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Sameer Badri Al-MhannaCenter for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, India.
Eric Tsz-Chun PoonDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong, China.
Barry A FranklinPreventive Cardiology and Cardiac Rehabilitation, Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA.
Mark A TarnopolskyDepartment of Pediatrics, McMaster University, Hamilton, ON, Canada.
John A HawleyExercise and Nutrition Research Program, The Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, VIC, Australia.
John M JakicicDepartment of Internal Medicine, Division of Physical Activity and Weight Management, Medical Center, University of Kansas, Kansas City, KS, USA.
Emmanuel StamatakisMackenzie Wearables Research Hub, Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
Jonathan P LittleSchool of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada.
Linda S PescatelloDepartment of Kinesiology, University of Connecticut, Storrs, CT, USA.
Deborah RiebeCollege of Health Sciences, University of Rhode Island, Kingston, RI, USA.
Walter R ThompsonCollege of Education and Human Development, Georgia State University, Atlanta, GA, USA.
James S SkinnerDepartment of Kinesiology, Indiana University Bloomington, Bloomington, IN, USA.
Sheri R ColbergHuman Movement Sciences Department, Old Dominion University, Norfolk, VA, USA.
Jonathan K EhrmanDivision of Cardiovascular Medicine, Department of Medicine, Henry Ford Health, Detroit, MI, USA.
George S MetsiosDepartment of Nutrition and Dietetics, University of Thessaly, Trikala, Greece.
Helen T DoudaDepartment of Physical Education and Sport Science, School of Physical Education, Sport Science and Occupational Therapy, Democritus University of Thrace, Komotini, Greece.
Norsuhana OmarDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. suhanakk@usm.my.
Abdullah F AlghannamLifestyle and Health Research Center, Health Sciences Research Center, Princess Nourah Bint Abdulrahman, University, Riyadh, Saudi Arabia.
Alexios BatrakoulisDepartment of Physical Education and Sport Science, School of Physical Education, Sport Science and Occupational Therapy, Democritus University of Thrace, Komotini, Greece. abatrakoulis@uth.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effects of high-intensity interval training (HIIT) on cardiometabolic health-related outcomes in patients with type 2 diabetes mellitus and concurrent overweight/obesity (diabesity).

designSystematic review and meta-analysis of randomized controlled trials (RCTs). DATA SOURCES: PubMed, Web of Science, Scopus, Science Direct, Cochrane Library, and Google Scholar databases were searched from inception up to January 31, 2025. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: RCTs comparing HIIT alone ≥ 2 weeks in duration with moderate-intensity continuous training (MICT). Participants were adults with diabesity.

resultsA total of 26 RCTs qualified, involving 790 patients (50/50 female/male ratio; age: 59.8 ± 12.9 years; body mass index: 28.9 ± 4.2 kg/m

conclusionsThe present findings suggest that HIIT may serve as an adjunctive non-pharmaceutical management solution for patients with diabesity. Open Science Framework registry: https://osf.io/9by24.

Indexed as

Aerobic capacityBlood pressureBody compositionExerciseGlucose metabolismIntermittent trainingLipid metabolismMetabolic syndrome

Identifiers

PMID40804647
PMCPMC12344893

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.