Evidence map›Paper›PMID 40805176›Full record

ReviewCancers2025

Combination of Irreversible Electroporation and

Zigeng Zhang, Guangbo Yu, Qiaoming Hou, Farideh Amirrad, Sha Webster, Surya M Nauli, Jianhua Yu, Vahid Yaghmai, Aydin Eresen, Zhuoli Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Oncology research · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zigeng ZhangDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.
Guangbo YuDepartment of Biomedical Engineering, University of California, Irvine, CA 92697, USA.
Qiaoming HouDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.
Farideh AmirradDepartment of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA.
Sha WebsterDepartment of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA.ORCID 0000-0002-9997-9081
Surya M NauliDepartment of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA.
Jianhua YuDepartment of Medicine, University of California, Irvine, CA 92868, USA.
Vahid YaghmaiDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.
Aydin EresenDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.ORCID 0000-0002-9414-9986
Zhuoli ZhangDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
MRI-Guided Dendritic-Cell-Based Vaccine Immunotherapy for Pancreatic CancerR01CA209886 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Vahid Yaghmai, Zhuoli Zhang · 2016 to 2026
$3.3M
Image-guided Interventional Combination Liver Cancer ImmunotherapyR01CA241532 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI YAGHMAI, VAHID, ZHANG, ZHUOLI · 2020 to 2024
$1.8M
NCI NIH HHS P30 CA062203NCI NIH HHS R01 CA209886NCI NIH HHS R01CA209886NCI NIH HHS R01 CA241532NCI NIH HHS R01CA241532
6 · The paper itself

Abstract

Colorectal liver metastasis (CRLM) poses a significant challenge in oncology due to its high incidence and poor prognosis in unresectable cases. Current treatments, including surgical resection, systemic chemotherapy, and liver-directed therapies, often fail to effectively target hypoxic tumor regions, which are inherently more resistant to these interventions. This review examines the potential of a novel therapeutic strategy combining irreversible electroporation (IRE) ablation and

Indexed as

artificial intelligenceClostridium novyi-NTcolorectal cancer liver metastasisirreversible electroporationmagnetic resonance imaging

Identifiers

PMID40805176
PMCPMC12346456

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.