Evidence mapPaperPMID 40806019Full record

SynthesisNutrients2025

Effect of Intermittent Fasting on Anthropometric Measurements, Metabolic Profile, and Hormones in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.

Yazan Ranneh, Mohammed Hamsho, Wijdan Shkorfu, Merve Terzi, Abdulmannan Fadel

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yazan RannehDepartment of Nutrition and Dietetics, College of Pharmacy, Al-Ain University, Abu-Dhabi P.O. Box 64141, United Arab Emirates.ORCID 0000-0001-9916-8468
Mohammed HamshoDepartment of Nutrition and Dietetics, Faculty of Health Science, Istanbul Yeni Yüzyıl University, Istanbul 34010, Turkey.ORCID 0009-0005-0408-3485
Wijdan ShkorfuDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Bahçeşehir University, Istanbul 34349, Turkey.ORCID 0009-0007-3757-9617
Merve TerziDepartment of Nutrition and Dietetics, Faculty of Health Science, Istanbul Yeni Yüzyıl University, Istanbul 34010, Turkey.ORCID 0000-0003-3397-9692
Abdulmannan FadelDepartment of Nutrition and Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain P.O. Box 1555, United Arab Emirates.ORCID 0000-0001-6042-8939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder characterized by excess body weight, hyperandrogenism, hyperglycemia, and insulin resistance often resulting in hirsutism and infertility. Dietary strategies have been shown to ameliorate metabolic disturbances, hormonal imbalances, and inflammation associated with PCOS. Recent evidence indicates that intermittent fasting (IF) could effectively enhance health outcomes and regulate circadian rhythm; however, its impact on PCOS remain unclear.

objectiveTherefore, this systematic review and meta-analysis aims to examine the effect of IF on women diagnosed with PCOS.

methodsComprehensive research was conducted across three major databases including PubMed, Scopus, and Web of Science without date restrictions. Meta-analysis was performed using Cochrane Review Manager Version 5.4 software.

resultsFive studies fulfilled the inclusion criteria. IF significantly reduced body weight (MD = -4.25 kg, 95% CI: -7.71, -0.79;

conclusionsIF represents a promising strategy for improving weight and metabolic, hormonal, and inflammatory profiles in women with PCOS. However, the existing evidence remains preliminary, necessitating further robust studies to substantiate these findings.

Indexed as

FastingHormonesMetabolomePolycystic Ovary SyndromeAdultAnthropometryBlood GlucoseBody Mass IndexFemaleHumansInsulinInsulin ResistanceIntermittent FastingBlood GlucoseHormonesInsulinhormonal profileintermittent fastingmeta-analysismetabolic profilePCOSpolycystic ovary syndrometime-restricted eating

Identifiers

PMID40806019
PMCPMC12348862

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.