Evidence map›Paper›PMID 40806267›Full record

ArticleInternational journal of molecular sciences2025

Serum Metabolomic Profiling Reveals Differences Between Systemic Sclerosis Patients with Polyneuropathy.

Kristine Ivanova, Theresa Schiemer, Annija Vaska, Nataļja Kurjāne, Viktorija Kenina, Kristaps Klavins

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristine IvanovaDepartment of Doctoral Studies, Rīga Stradinš University, LV-1050 Rīga, Latvia.ORCID 0000-0003-2127-2948
Theresa SchiemerBaltic Biomaterials Centre of Excellence, Headquarters at Riga Technical University, LV-1048 Rīga, Latvia.
Annija VaskaBaltic Biomaterials Centre of Excellence, Headquarters at Riga Technical University, LV-1048 Rīga, Latvia.ORCID 0000-0002-8724-6630
Nataļja KurjāneInstitute of Oncology and Molecular Genetics, Rīga Stradinš University, LV-1050 Rīga, Latvia.
Viktorija KeninaInstitute of Oncology and Molecular Genetics, Rīga Stradinš University, LV-1050 Rīga, Latvia.
Kristaps KlavinsBaltic Biomaterials Centre of Excellence, Headquarters at Riga Technical University, LV-1048 Rīga, Latvia.

Funding

RSU internal and RSU with LASE external consolidation 5.2.1.1.i.0/2/24/I/CFLA/005
6 · The paper itself

Abstract

Metabolome studies have already been carried out in patients with systemic sclerosis (SSc). However, polyneuropathy (PNP) as a complication of SSc has been overlooked in these studies. To the best of our knowledge, this is the first study to examine metabolic changes in SSc patients with PNP. Patients with SSc (

Indexed as

MetabolomeMetabolomicsPolyneuropathiesScleroderma, SystemicAdultAgedBiomarkersCase-Control StudiesChromatography, LiquidFemaleHumansMaleMiddle AgedBiomarkersmetabolic profilingmetabolomemodified polyneuropathymodified Rodnan skin scoreperipheral nerve systemRaynaud’s phenomenonsystemic sclerosis

Identifiers

PMID40806267
PMCPMC12346654

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.