Evidence mapPaperPMID 40806401Full record

ReviewInternational journal of molecular sciences2025

Circulating Biomarkers for the Early Diagnosis of Alzheimer's Disease.

Vharoon Sharma Nunkoo, Anamaria Jurcau, Mihaela Les, Alexander Cristian, Marius Militaru, Cristian Marge, Diana Carina Iovanovici, Maria Carolina Jurcau

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vharoon Sharma NunkooDoctoral School of Biomedical Sciences, University of Oradea, Universitatii Street nr 1, 410087 Oradea, Romania.ORCID 0000-0003-3708-3367
Anamaria JurcauDepartment of Psycho-Neurosciences and Rehabilitation, Faculty of Medicine and Pharmacy, University of Oradea, 1 Decembrie Square nr 10, 410073 Oradea, Romania.ORCID 0000-0002-0793-2877
Mihaela LesDoctoral School of Biomedical Sciences, University of Oradea, Universitatii Street nr 1, 410087 Oradea, Romania.
Alexander CristianDepartment of Psycho-Neurosciences and Rehabilitation, Faculty of Medicine and Pharmacy, University of Oradea, 1 Decembrie Square nr 10, 410073 Oradea, Romania.
Marius MilitaruDepartment of Neuroscience, "Victor Babeș" University of Medicine and Pharmacy, Eftimie Murgu Square nr 2, 300041 Timisoara, Romania.ORCID 0000-0003-3464-5782
Cristian MargeDepartment of Psycho-Neurosciences and Rehabilitation, Faculty of Medicine and Pharmacy, University of Oradea, 1 Decembrie Square nr 10, 410073 Oradea, Romania.
Diana Carina IovanoviciDoctoral School of Biomedical Sciences, University of Oradea, Universitatii Street nr 1, 410087 Oradea, Romania.ORCID 0000-0003-0135-6861
Maria Carolina JurcauFaculty of Medicine and Pharmacy, University of Oradea, 1 Decembrie Square nr 10, 410073 Oradea, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With a rapidly growing incidence and prevalence, Alzheimer's disease (AD) is rapidly becoming one of the most disabling, lethal, and expensive diseases of the century. To diagnose AD as early as possible, the scientific world struggles to find reliable and non-invasive biomarkers that could predict the conversion of mild cognitive impairment to AD and delineate the ongoing pathogenic vicious pathways to be targeted with therapy. Research supports the use of blood biomarkers, such as Aβ

Indexed as

Alzheimer DiseaseBiomarkersAmyloid beta-PeptidesEarly DiagnosisHumansPeptide Fragmentstau ProteinsAmyloid beta-PeptidesBiomarkersPeptide Fragmentstau ProteinsAlzheimer’s diseaseamyloid betablood-based biomarkersexosomesglial fibrillary acidic proteinmiRNAsneurofilament lightphosphorylated tau

Identifiers

PMID40806401
PMCPMC12347836

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.