Evidence map›Paper›PMID 40806571›Full record

ArticleInternational journal of molecular sciences2025

Inhibitory Effect of Allyl Isothiocyanate on Cariogenicity of

Tatsuya Akitomo, Ami Kaneki, Masashi Ogawa, Yuya Ito, Shuma Hamaguchi, Shunya Ikeda, Mariko Kametani, Momoko Usuda, Satoru Kusaka, Masakazu Hamada and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Phytochemistry and Application of White Mustard (Molecules (Basel, Switzerland) · 2026
    Review
  2. Isolation ofJournal of oral microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tatsuya AkitomoDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Ami KanekiDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Masashi OgawaDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Yuya ItoDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Shuma HamaguchiDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Shunya IkedaDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Mariko KametaniDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Momoko UsudaDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Satoru KusakaDepartment of Pediatric Dentistry, Hiroshima University Hospital, Hiroshima 734-8551, Japan.
Masakazu HamadaDepartment of Oral & Maxillofacial Oncology and Surgery, Graduate School of Dentistry, The University of Osaka, Suita 565-0871, Japan.
Chieko MitsuhataDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Katsuyuki KozaiDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Ryota NomuraDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.

Funding

JSPS KAKENHI 23K16205
6 · The paper itself

Abstract

Allyl isothiocyanate (AITC) is a naturally occurring, pungent compound abundant in cruciferous vegetables and functions as a repellent for various organisms. The antibacterial effect of AITC against various bacteria has been reported, but there are no reports on the effect on

Indexed as

Anti-Bacterial AgentsDental CariesIsothiocyanatesStreptococcus mutansBiofilmsGene Expression Regulation, Bacterialallyl isothiocyanateAnti-Bacterial AgentsIsothiocyanatesallyl isothiocyanatebacterial growthbacterial survivalRNA sequenceStreptococcus mutans

Identifiers

PMID40806571
PMCPMC12348008

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.