Evidence map›Paper›PMID 40807441›Full record

ArticleMolecules (Basel, Switzerland)2025

Garlic-Derived Allicin Attenuates Parkinson's Disease via PKA/p-CREB/BDNF/DAT Pathway Activation and Apoptotic Inhibition.

Wanchen Zeng, Yingkai Wang, Yang Liu, Xiaomin Liu, Zhongquan Qi

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wanchen ZengSchool of Medicine, Guangxi University, Nanning 530004, China.
Yingkai WangSchool of Medicine, Guangxi University, Nanning 530004, China.
Yang LiuSchool of Medicine, Guangxi University, Nanning 530004, China.
Xiaomin LiuSchool of Medicine, Guangxi University, Nanning 530004, China.
Zhongquan QiSchool of Medicine, Guangxi University, Nanning 530004, China.

Funding

the Guangxi Key R&D Program Project Gui Ke AB25069271the National Key Research and Development Program 2024YFA1107202the Natural Science Foundation of Guangxi 2024GXNSFAA010354the Natural Science Foundation of Guangxi 2025GXNSFAA0691007
6 · The paper itself

Abstract

Allicin (ALC), a naturally occurring organosulfur compound derived from garlic (

Indexed as

ApoptosisDopamine Plasma Membrane Transport ProteinsGarlicParkinson DiseaseSignal TransductionSulfinic AcidsAnimalsBrain-Derived Neurotrophic FactorCell Line, TumorCyclic AMP-Dependent Protein KinasesCyclic AMP Response Element-Binding ProteinDisease Models, AnimalDisulfidesHumansMaleMiceallicinBrain-Derived Neurotrophic FactorCyclic AMP-Dependent Protein KinasesCyclic AMP Response Element-Binding ProteinDisulfidesDopamine Plasma Membrane Transport ProteinsNeuroprotective AgentsOxidopamineSulfinic Acidsallicinapoptosisnetwork pharmacologyParkinson’s disease

Identifiers

PMID40807441
PMCPMC12348316

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.