Evidence map›Paper›PMID 40807445›Full record

ArticleMolecules (Basel, Switzerland)2025

Gold(III) Complexes with Aromatic Cyano-Substituted Bisdithiolate Ligands as Potential Anticancer and Antimicrobial Agents.

Dulce Belo, Sandra Rabaça, Sara G Fava, Sílvia A Sousa, Diogo Coelho, Jorge H Leitão, Teresa Pinheiro, Célia Fernandes, Fernanda Marques

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dulce BeloCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, Km 139.7, Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0001-8480-963X
Sandra RabaçaCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, Km 139.7, Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0002-5324-8013
Sara G FavaCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, Km 139.7, Bobadela, 2695-066 Loures, Portugal.
Sílvia A SousaiBB-Institute for Bioengineering and Biosciences, Associate Laboratory i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.ORCID 0000-0001-9291-9169
Diogo CoelhoiBB-Institute for Bioengineering and Biosciences, Associate Laboratory i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.
Jorge H LeitãoiBB-Institute for Bioengineering and Biosciences, Associate Laboratory i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.ORCID 0000-0001-8850-274X
Teresa PinheiroDepartamento de Engenharia e Ciências Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, Km 139.7, Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0002-1836-2603
Célia FernandesCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, Km 139.7, Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0002-2119-8293
Fernanda MarquesCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, Km 139.7, Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0001-8440-5299

Funding

Fundação para a Ciência e a tecnologia LA/P/0140/2020Fundação para a Ciência e a Tecnologia UIDB/04565/2020Fundação para a Ciência e a Tecnologia UID/Multi/04349/2019Fundação para a Ciência e a Tecnologia UIDP/04565/2020
6 · The paper itself

Abstract

Cancer and infectious diseases are major causes of global morbidity and mortality stressing the need to find novel drugs with promising dual anticancer and antimicrobial efficacy. Gold complexes have been studied for the past years due to their anticancer properties, with a few of them displaying antimicrobial properties, which support their pharmacological interest. Within this scope, we investigated six gold bisdithiolate complexes [Au (bdt)

Indexed as

Anti-Infective AgentsAntineoplastic AgentsCoordination ComplexesGoldCell Line, TumorFemaleHumansLigandsMicrobial Sensitivity TestsSulfhydryl CompoundsAnti-Infective AgentsAntineoplastic AgentsCoordination ComplexesGoldLigandsSulfhydryl Compoundsanticancerantimicrobialgold complexesgold dithiolatesmechanism of actionstructure activity relationship

Identifiers

PMID40807445
PMCPMC12348044

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.