Evidence map›Paper›PMID 40808673›Full record

ArticleMolecular therapy. Nucleic acids2025

Exploring adenosine analogs for chondrosarcoma therapy:

Marion Lenté, Juliette Aury-Landas, Mahdia Taieb, Benoît Bernay, Eva Lhuissier, Karim Boumédiene, Catherine Baugé

Abstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Biomolecules · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marion LentéUniversité de Caen Normandie, UR7451 BioConnect, 14000 Caen, France.
Juliette Aury-LandasUniversité de Caen Normandie, UR7451 BioConnect, 14000 Caen, France.
Mahdia TaiebUniversité de Caen Normandie, UR7451 BioConnect, 14000 Caen, France.
Benoît BernayUniversité de Caen Normandie, US Emerode, PROTEOGEN, 14000 Caen, France.
Eva LhuissierUniversité de Caen Normandie, UR7451 BioConnect, 14000 Caen, France.
Karim BoumédieneUniversité de Caen Normandie, UR7451 BioConnect, 14000 Caen, France.
Catherine BaugéUniversité de Caen Normandie, UR7451 BioConnect, 14000 Caen, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chondrosarcomas (CSs) are resistant to conventional chemotherapy and radiotherapy. Therefore, new therapeutic approaches are needed. The aim of this study was to validate the use of adenosine analogs as a new therapeutic strategy for the treatment of CS. Five adenosine analogs (aristeromycin, cladribine, clofarabine, formycin, and pentostatin) were evaluated

Indexed as

adenosine analogsapoptosiscell cyclecell deathchondrosarcomacladribineclofarabineMT: Oligonucleotides: Therapies and Applicationsproteomicstumor xenograft

Identifiers

PMID40808673
PMCPMC12346062

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.