Evidence map›Paper›PMID 40808794›Full record

ArticleJournal of oral biology and craniofacial research

Effect of calcium hydroxide and adipose-derived stem cell conditioned medium (ADSCs-CM) combination on reparative dentin formation in Wistar rats through RUNX-2 and OPN expression.

Radixtio Auzan Fepiosandi, Dian Agustin Wahjuningrum, Galih Sampoerno, Anuj Bhardwaj, Ajinkya M Pawar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Radixtio Auzan FepiosandiDoctoral Study Program in Dental Science, Faculty of Dental Medicine, Universitas Airlangga ,Jawa Timur, Indonesia.
Dian Agustin WahjuningrumDepartment of Conservative Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Jawa Timur, Indonesia.
Galih SampoernoDepartment of Conservative Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Jawa Timur, Indonesia.
Anuj BhardwajDepartment of Conservative Dentistry and Endodontics, College of Dental Science and Hospital, Rau, Indore, India.
Ajinkya M PawarDepartment of Conservative Dentistry and Endodontics, Nair Hospital Dental College, Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vital pulp exposure requires effective pulp capping to preserve the vitality and function of the dental pulp. Calcium hydroxide (Ca(OH) Objectives: To evaluate the effect of combining Ca(OH) Materials and methods: An in vivo experimental study was conducted using twelve healthy female Wistar rats ( Results: RUNX-2 and OPN expressions were significantly higher in the treatment group at all time points (p < 0.05), with peak levels observed on day 6. Histologically, the treatment group exhibited more homogeneous and better organized reparative dentin compared to the control group. Conclusion: The addition of ADSCs-CM to Ca(OH)

Indexed as

Adipose-derived stem cells conditioned mediumCalcium hydroxideMedicineOsteopontinReparative dentinRUNX-2

Identifiers

PMID40808794
PMCPMC12344247

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.