ArticleInternational journal of cardiology. Heart & vasculature2025
Association between epicardial adipose tissue imaging characteristics and left atrial appendage thrombus in patients with atrial fibrillation.
Article in International journal of cardiology. Heart & vasculature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- A Multicenter Prospective Study to Develop a Prediction Model for Postherpetic Neuralgia Using Clinical and Laboratory Indicators.Pain and therapy · 2026Article
- Recent highlights from theInternational journal of cardiology. Heart & vasculature · 2025Article
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Authors and funding
6 authors.
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Abstract
Aim: To explore the epicardial adipose tissue (EAT) characteristics associated with left atrial appendage thrombus (LAAT) in patients with atrial fibrillation (AF). Methods: This 1:1 individual-match (by age, sex, CHA Results: On contrast-enhanced CT, the mean CT attenuation of EAT was significantly higher in patients with LAAT than in those without at both 1 mm (median [IQR]: -75 [-88 to - 71] vs. - 71 [-86 to - 65.5], P < 0.01) and 3 mm (median [IQR]: -81 [-83.5 to - 78] vs. - 74 [-77.5 to - 72], P < 0.01) from the LAA boundary. However, no significant difference was observed at 5 mm (median [IQR]: -87 [-90 to - 85] vs. - 86 [-89 to - 83], P > 0.05). Relative EAT volume was not significantly associated with LAAT. Eight radiomic features were selected using least absolute shrinkage and selection operator (LASSO) regression to generate a radiomics score. The radiomics score was significant associated with LAAT, independent of clinical characteristics and traditional CT parameters of EAT. Conclusion: Imaging characteristics of EAT surrounding the LAA in patients with AF, particularly increased mean CT attenuation and radiomic features, were found to be associated with the presence of LAAT.
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