Evidence map›Paper›PMID 40809786›Full record

ArticlePhysics and imaging in radiation oncology2025

Multiparametric magnetic resonance imaging for radiotherapy response evaluation in high-risk soft tissue sarcoma: A pilot study.

Milan van Meekeren, Petra J van Houdt, Marta Fiocco, Jessica M Winfield, Christina Messiou, Birthe C Heeres, Hans Gelderblom, Neeltje Steeghs, Rick Haas, Kirsten van Langevelde

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Milan van MeekerenDepartment of Medical Oncology, Leiden University Medical Center, Leiden, the Netherlands.
Petra J van HoudtDepartment of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Marta FioccoMathematical Institue, Leiden University, Leiden, the Netherlands.
Jessica M WinfieldMRI Unit, Royal Marsden NHS Foundation Trust, Surrey, United Kingdom.
Christina MessiouMRI Unit, Royal Marsden NHS Foundation Trust, Surrey, United Kingdom.
Birthe C HeeresDepartment of Radiology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Hans GelderblomDepartment of Medical Oncology, Leiden University Medical Center, Leiden, the Netherlands.
Neeltje SteeghsDepartment of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Rick HaasDepartment of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Kirsten van LangeveldeDepartment of Radiology, Leiden University Medical Center, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Soft tissue sarcomas (STS) are rare mesenchymal tumors for which no clinically validated quantitative magnetic resonance imaging (qMRI) parameters exist yet.This study explores repeatability and association with histopathology of qMRI parameters during and after neo-adjuvant angiogenesis inhibition (oral pazopanib) and radiotherapy for localized, high-risk STS. Materials and methods: For fifteen patients, qMRI parameters, including apparent diffusion coefficient (ADC), volume transfer constant (K Results: RC was 0.17 × 10 Conclusion: This pilot study reported relatively low repeatability coefficients for ADC and T

Indexed as

Magnetic resonance imagingRadiotherapyRepeatabilitySoft tissue sarcomaTreatment response evaluation

Identifiers

PMID40809786
PMCPMC12347726

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.