ArticleNutrition research and practice2025
Interaction between chronotype and ultra-processed food intake on triglyceride-glucose index in Korean adults.
Article in Nutrition research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesChronotype and ultra-processed food (UPF) intake are individually associated with metabolic risk, but their combined effect remains unclear. This study examined the interaction between chronotype and UPF intake in relation to insulin resistance, assessed by the triglyceride-glucose (TyG) index. SUBJECTS/
methodsData were obtained from 542 adults in the Gangwon Obesity and Metabolic Syndrome (GOMS) Study. Chronotypes were classified into morning, intermediate, and evening types using Morningness-Eveningness Questionnaire-based clustering. UPF intake was assessed using a food frequency questionnaire and classified according to the Korean-adapted NOVA classification system. Intake was expressed as a percentage of total energy and divided into quartiles. General linear models were used to examine the interaction between chronotype and UPF intake in relation to the TyG index, with adjustments for relevant covariates. An additional analysis examined the association between TyG quartiles and diabetes prevalence.
resultsA significant interaction between UPF intake and chronotype was observed only in the evening-type group (
conclusionThe association between UPF intake and the TyG index varied by chronotype, with evening types showing greater vulnerability. These findings suggest that biological rhythms may modify the metabolic impact of diet, highlighting the need for personalized prevention strategies.
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