Evidence map›Paper›PMID 40810826›Full record

ArticleInternational journal of computer assisted radiology and surgery2025

A multi-view validation framework for LLM-generated knowledge graphs of chronic kidney disease.

Aditya Kumar, Dilpreet Singh, Mario Cypko, Oliver Amft

Abstract readValidation Study
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aditya KumarHahn-Schickard, 79110, Freiburg, Germany. aditya.kumar@hahn-schickard.de.ORCID http://orcid.org/0009-0002-0325-2505
Dilpreet SinghIntelligent Embedded Systems Lab, University of Freiburg, 79110, Freiburg, Germany.
Mario CypkoHahn-Schickard, 79110, Freiburg, Germany.
Oliver AmftHahn-Schickard, 79110, Freiburg, Germany.

Funding

Gemeinsame Bundesausschuss 01NVF21116
6 · The paper itself

Abstract

purposeThe goal of our work is to develop a multi-view validation framework for evaluating LLM-generated knowledge graph (KG) triples. The proposed approach aims to address the lack of established validation procedure in the context of LLM-supported KG construction.

methodsThe proposed framework evaluates the LLM-generated triples across three dimensions: semantic plausibility, ontology-grounded type compatibility, and structural importance. We demonstrate the performance for GPT-4 generated concept-specific (e.g., for medications, diagnosis, procedures) triples in the context of chronic kidney disease (CKD).

resultsThe proposed approach consistently achieves high-quality results across evaluated GPT-4 generated triples, strong semantic plausibility (semantic score mean: 0.79), excellent type compatibility (type score mean: 0.84), and high structural importance of entities within the CKD knowledge domain (ResourceRank mean: 0.94).

conclusionThe validation framework offers a reliable and scalable method for evaluating quality and validity of LLM-generated triples across three views: semantic plausibility, type compatibility, and structural importance. The framework demonstrates robust performance in filtering high-quality triples and lays a strong foundation for fast and reliable medical KG construction and validation.

Indexed as

Renal Insufficiency, ChronicHumansReproducibility of ResultsSemanticsChronic Kidney DiseaseExpert systemHealthcareKnowledge-driven modellingKnowledge graphsLLMsmedical informaticsModel-guided medicineNephrologySemantic evaluationTriplesValidation

Identifiers

PMID40810826
PMCPMC12689688

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.