Evidence map›Paper›PMID 40811145›Full record

ArticleHuman vaccines & immunotherapeutics2025

Analysis of three cases of disseminated BCG infection in infants after BCG vaccination in Beijing, China.

Li Li, Jingyi Xu, Jianlin Cai, Mei Wang, Fang Wang, Liqing Yang, Yunhua Bai, Bin Jia, Shuping Li

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Li LiImmunization Program Department, Chaoyang District Center for Disease Control and Prevention, Beijing, China.
Jingyi XuImmunization Program Department, Chaoyang District Center for Disease Control and Prevention, Beijing, China.
Jianlin CaiImmunization Program Department, Chaoyang District Center for Disease Control and Prevention, Beijing, China.
Mei WangImmunization Program Department, Chaoyang District Center for Disease Control and Prevention, Beijing, China.
Fang WangImmunization Program Department, Chaoyang District Center for Disease Control and Prevention, Beijing, China.
Liqing YangImmunization Program Department, Chaoyang District Center for Disease Control and Prevention, Beijing, China.
Yunhua BaiImmunization Program Department, Chaoyang District Center for Disease Control and Prevention, Beijing, China.
Bin JiaImmunization Program Department, Chaoyang District Center for Disease Control and Prevention, Beijing, China.
Shuping LiImmunization Program Department, Chaoyang District Center for Disease Control and Prevention, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report and analyze three cases of disseminated BCG infection in infants after BCG vaccination that occurred between 2022 and 2024 in Chaoyang District, Beijing, which were the only three monitored during the clinical application we conducted. All the patients had primary immunodeficiency disease (PID). Two cases had defects in the JAK3 and TNFRSF13B genes; one case had multiple gene defects in CR2, IFNAR2, TLR2, and exon 13 of DOCK11. Disseminated BCG infection is a rare adverse reaction after BCG vaccination. It occurs almost exclusively in immunodeficient infants or children. Although it rarely occurs, it is necessary to pay more attention to clinical practice because of its serious consequences.

Indexed as

BCG VaccineTuberculosisVaccinationBeijingChinaFemaleHumansInfantJanus Kinase 3MaleMycobacterium bovisPrimary Immunodeficiency DiseasesBCG VaccineJanus Kinase 3BCG vaccinecausal associationDisseminated BCG infectionprimary immunodeficiency disease

Identifiers

PMID40811145
PMCPMC12355699

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.