Evidence map›Paper›PMID 40812352›Full record

ArticleGeriatrics & gerontology international2025

Loneliness and isolation: Are they associated with the wish for an earlier end of life?

André Hajek, Larissa Zwar, Razak M Gyasi, Dong Keon Yon, Supa Pengpid, Karl Peltzer, Hans-Helmut König

Abstract read
In one paragraph

Article in Geriatrics & gerontology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

André HajekDepartment of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Hamburg Center for Health Economics, Hamburg, Germany.ORCID https://orcid.org/0000-0002-6886-2745
Larissa ZwarDepartment of Psychology, Brock University, St. Catharines, Ontario, Canada.
Razak M GyasiAfrican Population and Health Research Center, Nairobi, Kenya.
Dong Keon YonCenter for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
Supa PengpidDepartment of Health Education and Behavioral Sciences, Faculty of Public Health, Mahidol University, Bangkok, Thailand.
Karl PeltzerDepartment of Health Education and Behavioral Sciences, Faculty of Public Health, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-5980-0876
Hans-Helmut KönigDepartment of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Hamburg Center for Health Economics, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine the association of loneliness and social isolation with the desired age at death among middle-aged and older adults in Germany.

methodsData were taken from the German Aging Survey (wave 8: nationally representative sample of community-dwelling individuals aged ≥43 years; n = 3826). The mean age equaled 69.3 years (SD 11.3 years, 43-99 years). Loneliness and social isolation were both quantified using psychometrically sound and widely used tools. Several sociodemographic, lifestyle-related and health-related covariates were included in linear regression analysis (with robust standard errors).

resultsThe mean desired age at death was 90.1 years (SD 8.0 years). Regressions showed that there was a robust association of loneliness (β = -1.47, P < 0.001) and social isolation (β = -1.49, P < 0.001) with lower desired age at death among the total sample, even after adjusting for a wide array of covariates. In the fully-adjusted model, such associations were also present among both men and women (with significant sex differences for the association between loneliness and the outcome; i.e., more pronounced association between loneliness and the desired age at death among men).

conclusionsLoneliness (among men in particular) and social isolation were both associated with a lower desired age at death. This stresses the importance of tackling loneliness and social isolation in later life. It is of note that this is the very first study examining the association of loneliness and social isolation with the desired age at death. Thus, it can serve as a basis for future studies. Geriatr Gerontol Int 2025; 25: 1412-1417.

Indexed as

Attitude to DeathLonelinessSocial IsolationAdultAgedAged, 80 and overFemaleGermanyHumansMaleMiddle Ageddepressiondesired age at deathlife expectancylonelinesssocial isolationsuicidal ideationwish to die earlier

Identifiers

PMID40812352
PMCPMC12501667

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.