ArticleBMC nephrology2025
Trends in chronic kidney disease mortality among patients with systemic lupus erythematosus: a U.S. population-based study (1999-2020).
Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Divergence between initial and cumulative manifestations in systemic lupus erythematosus: effect of age and sex in a prospective lupus cohort from Pakistan.Annals of medicine and surgery (2012) · 2026Article
- Screening of diagnostic biomarkers for taurine metabolism-related genes in lupus nephritis and analysis of immune infiltration.International urology and nephrology · 2026Article
- Risk of chronic kidney disease in newly diagnosed SLE with preserved renal function: a national study.Rheumatology (Oxford, England) · 2026Article
- Long-term mortality trends in patients with concurrent hernia and diabetes in the United States.Frontiers in endocrinology · 2026Article
- Mortality trends in the United States for adults with concurrent cerebrovascular disease and pulmonary embolism.Frontiers in neurologyArticle
Corrections and comments
- Correction · 2026-03-18Concerns/Issues about Data · Error in Text · Updated to Retraction · · correction langauge overwritten, infoormation taken from internet archive: https://web.archive.org/web/20260324131855/https://link.springer.com/article/10.1186/s12882-026-04846-9
- Expression of concern · 2026-01-14Concerns/Issues about Data · Updated to Correction · Updated to Retraction ·
- Retraction · 2026-07-07Concerns/Issues about Data · Concerns/Issues about Methods · Concerns/Issues about Results and/or Conclusions · Investigation by Journal/Publisher · Investigation by Third Party · Results Not Reproducible · Unreliable Results and/or Conclusions · Upgrade/Update of Prior Notice(s) ·
- Erratum issued
- Expression of concern
- Retracted
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite advancements in treatment, chronic kidney disease (CKD) remains a major cause of morbidity and mortality in systemic lupus erythematosus (SLE). However, a comprehensive analysis of mortality trends and demographic disparities remains limited. This study aims to evaluate mortality related to CKD among patients diagnosed with SLE, acknowledging that the specific cause of CKD (e.g., lupus nephritis vs. other etiologies) cannot be determined from available data.
methodsThe CDC WONDER database was used to obtain mortality data for U.S. adults (≥ 25 years) due to chronic renal failure in SLE from 1999 to 2020. Crude and age-adjusted mortality rates (AAMRs) per 100,000 individuals were calculated and stratified by gender, race, year, state, census region, urbanization, and place of death. Trends in AAMRs were evaluated using Joinpoint regression to estimate annual percent change (APC) and average annual percent change (AAPC).
resultsBetween 1999 and 2020, a total of 5204 deaths were attributed to chronic renal failure in patients with SLE. The overall AAMR for CKD in SLE patients increased from 0.076 to 0.104 during this period, with a pronounced rise from 2018 to 2020 (APC: 15.06). Females exhibited higher AAMR than males (0.116 vs. 0.013). Additionally, AAMRs were highest among non-Hispanic (NH) African Americans and lowest among NH Whites (0.265 vs. 0.036). Regionally, the highest AAMRs were recorded in the West, South Carolina, and Metropolitan areas. The highest crude death rate (CDR) was observed in the 55–85 + age group.
conclusionsMortality from CKD among patients with SLE has risen over the past two decades, especially from 2018 to 2020. These discrepancies underscore the need for targeted healthcare strategies and legislative measures to reduce the growing mortality burden.
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