Evidence mapPaperPMID 40814743Full record

Observational studyJournal of diabetes2025

Trends, Social Determinants, and Lifestyle Factors Associated With Comorbidity of Diabetes and Kidney Diseases Among Chinese Adults Aged ≥ 45 Years.

Guanghui Cui, Shaojie Li, Yu Qin, Yuqin Zhang, Kunpeng Hui, Mengfan Feng, Weiwei Li, Xuezhi Zhang

Abstract readObservational Study
In one paragraph

Observational study in Journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Diabetic Kidney Disease Update.Journal of diabetes · 2025
    Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guanghui CuiDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Beijing, China.
Shaojie LiSchool of Public Health, Peking University, Beijing, China.
Yu QinDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Beijing, China.
Yuqin ZhangDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Beijing, China.
Kunpeng HuiDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Beijing, China.
Mengfan FengDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Beijing, China.
Weiwei LiDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Beijing, China.
Xuezhi ZhangDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-4564-7989

Funding

Clinical Research Funding for High-Level Hospitals (Peking University First Hospital Youth Clinical Research Special Program) 2023YC32National Collaborative Project on Chronic Disease Management in Traditional Chinese and Western Medicine CXZH2024154Qi-Huang Scholar Chief Scientist Program of the National Administration of Traditional Chinese Medicine Leading Talents Support Program 2021Shanxi Provincial Administration of Traditional Chinese Medicine Research Project 2024ZYY2C132
6 · The paper itself

Abstract

objectivesThe dual burden of diabetes and kidney disease poses a growing public health challenge in aging populations, yet its longitudinal trends and modifiable determinants in China remain understudied. This study aims to track the trends in the prevalence of the comorbidity of diabetes and kidney disease in Chinese middle-aged and older adults over a 10-year period (2011-2020) and identify social determinants and lifestyle factors associated with this comorbidity.

methodsThis study utilized data from five waves of the China Health and Retirement Longitudinal Study (CHARLS). Temporal trends and geographical distributions of the comorbidity of diabetes and kidney diseases were analyzed across survey years; disaggregated by sex, residence, and geographical region. Cox proportional hazards regression models were employed to explore the associations between SDOH burden, lifestyle factors, and the risk of comorbidity.

resultsThe prevalence of diabetes and kidney disease comorbidity exhibited a clear upward trend among Chinese adults aged ≥ 45 years, increasing from 0.60% in 2011 to 3.10% in 2020. Geographical analysis revealed significant regional disparities, with Northeast China having the highest prevalence throughout the decade (4.76% in 2020). High SDOH burden was associated with an increased risk of comorbidity (HR = 1.24, 95% CI = 1.01-1.52). Conversely, maintaining a good (HR = 0.38, 95% CI = 0.27-0.54) or moderate (HR = 0.74, 95% CI = 0.59-0.91) lifestyle was associated with a reduced risk.

conclusionThe rising prevalence and significant regional disparities of diabetes and kidney disease comorbidity underscore the urgent need for targeted public health interventions in China.

Indexed as

Diabetes MellitusKidney DiseasesLife StyleSocial Determinants of HealthAgedChinaComorbidityEast Asian PeopleFemaleHumansLongitudinal StudiesMaleMiddle AgedPrevalenceRisk FactorsChinacomorbiditydiabeteskidney diseaselifestylessocial determinants

Identifiers

PMID40814743
PMCPMC12355039

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.