SynthesisProbiotics and antimicrobial proteins2026
Effects of Probiotics on Markers of Oxidative/Nitrosative Stress and Damage Associated with Inflammation in Non-communicable Diseases: A Systematic Review and Meta-analysis of Randomized Placebo-Controlled Trials.
Synthesis in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Trial
- Oxidative Stress-Gut Microbiome Crosstalk: Intestinal Redox Imbalance and Probiotics Therapeutic Potential.Antioxidants (Basel, Switzerland) · 2026Review
- Probiotic supplementation and postoperative antioxidant response in patients undergoing open‑heart surgery: a randomized controlled trial.Cardiovascular endocrinology & metabolism · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammation and oxidative/nitrosative stress (O&NS) are serious complications in non-communicable diseases (NCDs), including endocrine and metabolic and neurodegenerative diseases. The beneficial probiotic microbes, such as Lactobacillus, Bifidobacterium, and Streptococcus, can decrease O&NS and inflammation. We conducted this systematic review and meta-analysis of randomized controlled trials (RCTs) with aims to elucidate the effects of probiotics on O&NS and inflammation in NCDs. A systematic search of PubMed, Scopus, and EMBASE resulted in the inclusion of studies if they met the eligibility criteria. Methodological quality was assessed using the Cochrane Risk of Bias 2 tool. Data (combined effect size) were analyzed using Meta-Essentials software. Fifteen studies/16 trials with a total of 807 participants (421 cases/386 controls) were reviewed. There was high and moderate certainty of evidence (GRADE) for the effectiveness of probiotic intervention (vs. placebo) in increasing (↑) glutathione (GSH) levels (SMD(SE) = 0.89 (0.51)/p < 0.05, 95%CI - 0.23 to 2.1, I
Indexed as
Identifiers
40815363What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.