ReviewReproductive sciences (Thousand Oaks, Calif.)2025
Long Non-Coding, Micro, and Circular RNAs in Ovarian Cancer Metastasis: Pathways and Treatment Approaches.
Review in Reproductive sciences (Thousand Oaks, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gynaecologic cancer is a major cause of death for women and the most well-known ovarian cancer (OC) has a high mortality rate. Given that the majority of ovarian cancer deaths are caused by metastatic tumors that have spread to nearby tissues, several biological processes, including angiogenesis and metastasis, have a role in the onset and course of these diseases. Numerous non-coding RNAs (ncRNAs) have been shown in recent studies to contribute to the invasion and metastasis of ovarian cancer by altering particular cellular pathways. Three forms of ncRNAs which are long non-coding RNAs, micro RNAs, and circular RNAs are the subjects of this review. miRNA is used as a potential biomarker such as miR-375 which is a serum exosome and also in therapeutics. lncRNA sponges with miRNA which sequesters and regulates tumor progression such as XIST miR-149-3p. circRNA targets proteins and regulates gene expression. This review provides an overview of the precise function of non-coding RNAs in the many pathways and molecular exchanges that contribute to the invasion and metastasis of malignancies. To increase the survival rate of OC patients, new approaches to ncRNA-targeted therapy are being utilised, including targeting lncRNAs and circRNAs and modulating the tumor microenvironment using exosomes.
Indexed as
Identifiers
40815436What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.