Evidence map›Paper›PMID 40815683›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Ionocyte CFTR Coordinates Chloride Absorption and Secretion to Balance Airway Fluid.

Feng Yuan, Javahir Hajibabazade, Yaling Yi, Adriane E Thompson, Lianwu Fu, Yan Zhang, Ziyuan Wang, Yinghua Tang, Grace N Gasser, Meihua Hao and 3 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Pulmonary Ionocytes at the Crossroads of Absorption and Secretion: Clues from the Ferret.American journal of respiratory and critical care medicine · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Feng YuanDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.ORCID 0000-0002-5210-8510
Javahir HajibabazadeDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Yaling YiDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Adriane E ThompsonDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Lianwu FuGregory Fleming James Cystic Fibrosis Research Center, and.
Yan ZhangDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Ziyuan WangStem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, California.
Yinghua TangDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Grace N GasserDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Meihua HaoDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine.
Ziying YanDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Xingshen SunDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
John F EngelhardtDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.ORCID 0000-0003-2389-9277

Funding

UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMIT GAGGAR · 2007 to 2026
$23.0M
Biology of Submucosal Gland Stem Cells in the AirwayR01HL165404 · NHLBI · UNIVERSITY OF IOWA · PI ENGELHARDT, JOHN F · 2022 to 2025
$2.9M
EOI:: IMPLEMENTING THE PRESIDENT'S DEPARTMENT OF GOVERNMENT EFFICIENCY COST EFFICIENCY INITIATIVE (MARCH 19, 2025)::EOI BILATERAL MODIFICATION TO DESCOPE WORK FOR NATIONAL FERRET RESOURCE AND RESEARC75N92025C00007 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RIMMER, JAMES · 2025 to 2025
$1.4M
Cystic Fibrosis Foundation 001478XX220Cystic Fibrosis Foundation ENGELH21XX0Cystic Fibrosis Foundation SUN22G0Cystic Fibrosis Foundation YAN23G0Cystic Fibrosis Foundation YUAN24G0Cystic Fibrosis Research 1267026NHLBI NIH HHS R01 HL165404NIDDK NIH HHS P30 DK072482NIH HHS 75N92025C00007
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChloridesCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorLungAnimalsAnimals, Genetically ModifiedFerretsIon TransportChloridesCystic Fibrosis Transmembrane Conductance Regulatorairway stem cellscystic fibrosispulmonary ionocytestransgenic ferrets

Identifiers

PMID40815683
PMCPMC12555048

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.