Trial reportJournal of neurology2025
Improving conscientiousness through a smartphone app and telecoaching intervention: insights from multiple sclerosis and healthy aging samples.
Trial report in Journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Understanding the Unmet Needs of People with MS at Diagnosis and Throughout Their Care Journey: Insights from a Survey-Based Study.Neurology and therapy · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Lower Conscientiousness is associated with cognitive decline, unemployment, and poorer health outcomes in both neurological and aging populations. This study evaluated a smartphone-based intervention to enhance Conscientiousness in people with multiple sclerosis (PwMS) and healthy aging (HA) adults. Initially, 38 PwMS and 22 HA participants completed baseline assessments (cognitive, personality, depression, and anxiety measures). Attrition and disease factors left 24 PwMS and 20 HA adults at the 12-week follow-up. Participants randomly assigned to the intervention arm received the "Conscientiousness Coach" app, which combined value identification, SMART goal development, smartphone-based tracking, and scheduled telehealth coaching sessions, whereas controls were wait-listed. ANCOVA for baseline scores showed a significant treatment effect on NEO-FFI Conscientiousness (p = 0.015) that remained after substituting age for diagnosis (p = 0.029). A lack of significant effects for group (PwMS vs. HA) and age indicated that treatment impact was consistent across both samples. Within the intervention group, paired-sample t-tests revealed large gains in the Conscientiousness domain (d = 0.93, p < 0.001) and moderate improvements in the Orderliness (d = 0.67, p = 0.007) and Dependability (d = 0.52, p = 0.030) facets, with no change in wait-list controls. No treatment effects emerged for Neuroticism, depression, or anxiety, underscoring the trait-specific nature of the intervention. Results suggest that targeted digital interventions can favorably impact personality and enhance quality of life. Future study will examine use of AI to replace the behavioral coaching component of this intervention and its long-term impact on personality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.