ArticleBMC complementary medicine and therapies2025
Herbal medicine evaluation for reimbursement-based facial palsy (HERB-FP): a retrospective analysis using Korean health insurance claim data 2020-2024.
Article in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundFacial palsy (FP) is a neurological condition marked by unilateral facial weakness due to facial nerve dysfunction. In November 2020, the Korean government launched a pilot reimbursement program for herbal decoctions, expanding insurance coverage to include treatments traditionally excluded from the national health system. This study aimed to evaluate the real-world utilization, clinical effectiveness, and safety of herbal medicine (HM) for FP within this national reimbursement program.
methodsThis retrospective study analyzed outpatient claims data from the Health Insurance Review and Assessment Service (HIRA) between November 2020 and April 2024. Patients diagnosed with FP (KCD code G51.0) from January 2018 onward who received treatment at Korean Medicine (KM) clinics participating in the program were included. Patients were excluded if they had fewer than two visits or incomplete treatment records. Descriptive and inferential analyses were conducted to examine patient demographics, treatment patterns, symptom progression, and adverse events (AEs).
resultsA total of 3,927 patients were analyzed (2,174 females and 1,753 males; mean age: 54.2 ± 14.7). Peripheral FP was reported in 88.9% of cases. Most patients received treatment in outpatient KM clinics, with 56.2% making two or fewer visits and 36.6% initiating care within two weeks of symptom onset. Ligigeopoong-san (17.0%) and Gamiboik-tang (14.4%) were the most commonly prescribed formulas. Among patients with symptom severity scores at both baseline and follow-up (n = 2,161), 49.2% showed improvement, 45.6% remained unchanged, and 5.2% worsened. The overall AE rate was low (1.76%), with gastrointestinal issues being most frequent.
conclusionsHerbal decoctions prescribed under the Korean pilot reimbursement program for FP showed a low incidence of adverse events and moderate rates of symptom improvement, suggesting a potentially safe and effective treatment option based on large-scale real-world data. These findings support the continued integration of herbal medicine into national health policy. However, limitations include the absence of clinical grading and reliance on administrative data. As the second-phase program expands in scope and duration, further research should explore its long-term clinical and economic outcomes to guide evidence-based healthcare policy development.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.