Evidence map›Paper›PMID 40817738›Full record

ReviewCytoskeleton (Hoboken, N.J.)2026

Centrosome-Signaling Pathway Crosstalk: A Core Hub From Cellular Homeostasis to Disease.

Mingyu Pan, Jinghan Li, Jingyan Fu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cytoskeleton (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mingyu PanState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.
Jinghan LiState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.
Jingyan FuState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0002-5896-8132

Funding

2115 Talent Development Program of China Agricultural UniversityChina Agricultural University Young Talent Program in Life Science 002Innovative Project of the State Key Laboratory of Animal Biotech Breeding 2024SKLAB1-7Ministry of Science and Technology of the People's Republic of China 2022YFC3401100National Natural Science Foundation of China 31970662National Natural Science Foundation of China 32170700National Natural Science Foundation of China 32450783
6 · The paper itself

Abstract

The centrosome, an evolutionarily conserved organelle in most animal cells, plays a pivotal role in fundamental processes such as cell division and ciliogenesis. Recent evidence increasingly highlights active crosstalk between the centrosome and the signaling pathways, through which cells dynamically detect and respond to diverse extracellular and intracellular cues. In this review, we summarize the roles of the centrosome in multiple signaling pathways, including Hedgehog, Wnt, and Notch that govern cellular growth, division, differentiation, and tissue homeostasis. We also explore how these interactions mold centrosomal behavior, emphasizing its function as a hub for signaling integration.

Indexed as

CentrosomeHomeostasisSignal TransductionAnimalsHumans

Identifiers

PMID40817738
PMCPMC13485233

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.