Observational studyBMC geriatrics2025
"The association of cardiometabolic diseases and related medications with cognitive performance: a cross-sectional observational study from Central Poland".
Observational study in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Investigating the impact of migraine on short-term and working memory: a systematic review and meta-analysis.Journal of neurology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionGlobal ageing, the rising prevalence of cardiometabolic diseases and dementia becomes increasingly important public health topic. This relation has evoked extensive research efforts aimed at finding the link between cardiovascular health and cognitive decline. Cardiometabolic medications, widely prescribed for their beneficial effects on vascular health, are being closely examined for their potential influence on cognitive health and their capacity to modify the risk of dementia.
methodsIn this cross-sectional study, 1735 individuals from Central Poland were investigated on cardiometabolic diseases, treatments, and cognitive function. Cognitive performance was evaluated using the Mini-Mental State Examination (MMSE) dichotomized to ≥ 24 points and < 24 points.
resultsThe logistic regression revealed a strong association between age (OR:1.07, 95% CI 1.05-1.08, p < 0.001) and stroke (OR:1.43, 95% CI 1.30-1.84, p < 0.001) with worse MMSE dichotomized score. Similarly, insulin usage was linked to an increased risk of low MMSE (OR:1.33, 95%CI: 1.06-1.73, p = 0.008). In contrast, BMI (OR:0.96, 95%CI 0.94-0.98, p = 0.001), lipid disorders (OR:0.69, 95% CI 0.48-0.92, p = 0.01), use of calcium channels blockers (OR:0.71, 95% CI 0.48-0.94, p = 0.04), alpha-blockers (OR:0.54, 95% CI 0.23-0.86, p = 0.004) and angiotensin II receptor antagonists (OR 0.56, 95% CI 0.29-0.83, p = 0.001), were associated with normal cognitive functions (R
conclusionsThe results present the complex connection between cardiometabolic disorders, their treatment and cognitive functioning. The research highlights the necessity for a tailored approach in prescribing cardiovascular medications, considering their potential link with cognitive health. Especially the role of angiotensin II receptor antagonists merits further studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.