ArticleBMC geriatrics2025
Association between basal metabolic rate and cognitive function in Chinese older adults: the mediating effect of sarcopenia.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Associations of Dietary Antioxidant and Phytochemical Indices with Cognitive Function: Mediating Roles of Basal Metabolic Rate and Systemic Inflammation.Antioxidants (Basel, Switzerland) · 2026Article
- Household fuel use, social engagement, and cognitive decline in older Chinese adults: a prospective cohort study based on CHARLS.BMC geriatrics · 2026Observational
- Basal metabolic rate predicts dementia in community-dwelling older adults: a 5-year longitudinal study.European geriatric medicine · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundCognitive aging poses a major worldwide health concern. The association between basal metabolic rate (BMR) and cognition isn't well understood. This research examines sarcopenia's potential role as a mediator: linking BMR to cognitive function.
methodsAnalysis used China Health and Retirement Longitudinal Study (CHARLS) data from adults aged ≥ 60 years (2015, 2018 waves). Mental integrity and episodic memory recall assessed cognitive function. Linear multivariate analyses were conducted to examine the associations between BMR, sarcopenia, and cognitive function, adjusting for potential confounders. Mediation analyses explored sarcopenia's role in the BMR-cognitive function relationship. Restricted cubic splines assessed nonlinear relationships, and subgroup analyses evaluated group heterogeneity.
resultsLongitudinal linear multivariate modeling, after covariate adjustment, demonstrated a significant positive association linking BMR to cognitive function (β = 1.23, 95% CI: 0.25-2.21, P = 0.014). Sarcopenia showed an inverse relationship with cognitive function (β = - 0.75, 95% CI: -1.11- -0.40, P < 0.001). Critically, sarcopenia mediated 26.98% of BMR's total effect on cognitive function, with an indirect effect of 5.27 × 10⁻⁴ (95% CI: 8.61 × 10⁻⁴- 1.54 × 10⁻³). Subgroup analysis indicated that smoking status and place of residence had significant effects on the relationship between basal metabolic rate and cognitive function.
conclusionsThe study found that BMR is positively associated with cognitive function, whereas sarcopenia is inversely associated with cognitive function and mediates the BMR- cognitive function association.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.