Evidence mapPaperPMID 40820145Full record

ArticleScientific reports2025

One anastomosis gastric bypass produces considerable weight reduction and resolution of medical complications with an acceptable rate of nutritional deficiencies.

Wiaam Al-Hasani, Ruvini Ranasinghe, Yip Han Chin, Han Shi Jocelyn Chew, Tina Mazahiri, Nalinda Herath, Fannie Lajeunesse-Trempe, Pia Roser, Starlene Grady, Amy Lee and 5 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wiaam Al-Hasani *Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK.
Ruvini Ranasinghe *Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK.
Yip Han ChinYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Han Shi Jocelyn ChewAlice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Tina MazahiriDepartment of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK.
Nalinda HerathDepartment of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK.
Fannie Lajeunesse-TrempeQuebec Heart and Lung Institute, Laval University, Quebec, Canada.
Pia RoserSchool of Life Course Sciences, King's College London, London, UK.
Starlene GradyUpper GI Surgery & Bariatric Surgery, Princess Royal University Hospital, Orpington, UK.
Amy LeeUpper GI Surgery & Bariatric Surgery, Princess Royal University Hospital, Orpington, UK.
Randolf AltmeyerDepartment of Mathematics, Imperial College London, London, UK.
Nicholas W S ChewYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Royce P VincentDepartment of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK.
Shamsi El-HasaniUpper GI Surgery & Bariatric Surgery, Princess Royal University Hospital, Orpington, UK.
Georgios K DimitriadisDepartment of Endocrinology ASO/EASO COM, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK. georgios.dimitriadis@kcl.ac.uk.ORCID http://orcid.org/0000-0002-6662-804X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One anastomosis gastric bypass (OAGB) is a relatively novel bypass surgery variant, increasingly used as a primary surgical procedure. A total of 101 patients (mean age 44.7 ± 10.7 years, mean BMI 47.2 ± 6.6 kg/m2) underwent OAGB between 2014 and 2019 in a single institution. Results obtained 6,12 and 24 months postoperatively were compared with the pre-operative values using "Analyse-it software v5.40.2" and Graphpad Prism v9.3 for figures and tables. Data were tested for normality, described as Mean ± SD, compared using paired sample t-test with 5% p-value for significance and 95% confidence interval (CI). A significant body mass index (BMI), haemoglobin A1c (HbA1c) and low-density lipoprotein (LDL) reduction was recorded throughout follow-up period, with greatest improvement seen 2 years after surgery (47.6 ± 22 kg/m2 vs. 29.4 ± 6.4 kg/m2 ,6.7 ± 1.8% vs. 5.5 ± 0.2% and 3.2 ± 1 vs. 2.05 + 0.7 mmol/ l, p < 0.05). The number of glucose-lowering drugs decreased from 1.6 ± 0.9 to 0.3 ± 0.4 at 24-months, p < 0.001. The rates for zinc, ferritin, folate, B12 and vitamin D deficiency at 24-months were: 8.9%,4%, 5.9%, 0% and 3% respectively. OAGB can effectively downstage obesity disease and improve glucose and lipid homeostasis with a low risk for nutritional deficiencies. This study is one of few to report specifically on the frequency and type of nutritional deficiencies following OAGB surgery.

Indexed as

Gastric BypassMalnutritionObesity, MorbidPostoperative ComplicationsWeight LossAdultBody Mass IndexFemaleGlycated HemoglobinHumansMaleMiddle AgedTreatment OutcomeGlycated HemoglobinBariatric surgeryHyperlipidaemiaNutritional deficiencyObesityObstructive sleep apnoeaOne anastomosis gastric bypassT2DM

Identifiers

PMID40820145
PMCPMC12358596

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.