Evidence map›Paper›PMID 40820436›Full record

ArticleThe International journal of eating disorders2025

The Hidden Spectrum Within Eating Disorders: Clustering Neurodivergent Traits and Sensory Sensitivity.

Paolo Meneguzzo, Marta Magno, Alice Garolla, Elisa Bonello, Elena Tenconi, Patrizia Todisco

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Article in The International journal of eating disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paolo MeneguzzoDepartment of Neuroscience, University of Padova, Padova, Italy.ORCID 0000-0003-3323-6071
Marta MagnoEating Disorder Unit, Casa di Cura "Villa Margherita"-Neomesia, Arcugnano, Italy.ORCID 0000-0002-0400-774X
Alice GarollaEating Disorder Unit, Casa di Cura "Villa Margherita"-Neomesia, Arcugnano, Italy.
Elisa BonelloEating Disorder Unit, Casa di Cura "Villa Margherita"-Neomesia, Arcugnano, Italy.
Elena TenconiDepartment of Neuroscience, University of Padova, Padova, Italy.ORCID 0000-0003-1629-9871
Patrizia TodiscoEating Disorder Unit, Casa di Cura "Villa Margherita"-Neomesia, Arcugnano, Italy.ORCID 0000-0002-2212-9855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEmerging research suggests that autistic traits and sensory sensitivities are prevalent among individuals with eating disorders (EDs), particularly females. Traditional diagnostic approaches may overlook the heterogeneity of neurodevelopmental features within this population. A person-centered approach could uncover meaningful subgroups and guide individualized treatment strategies. This study aimed to identify neurocognitive profiles among cisgender female ED patients, focusing on autistic traits, sensory sensitivity, social cognition, and clinical severity, through a dimensional and person-centered clustering approach.

methodA total of 164 cisgender female patients were assessed using the Autism Spectrum Quotient (AQ-10), Girls Questionnaire for Autism Spectrum Condition (GQ-ASC), Sensory Perception Quotient (SPQ-10), Story-based Empathy Task (SET), and clinical measures including the Eating Disorder Examination Questionnaire (EDE-Q), Body Uneasiness Test (BUT), and Symptom Checklist-90-Revised (SCL-90-R). Hierarchical cluster analysis (Ward's method) was conducted on standardized scores. Between-cluster comparisons and multinomial logistic regression assessed the robustness and predictive validity of the cluster solution.

resultsFour distinct clusters emerged, differing significantly in autistic traits, sensory sensitivity, social cognition, and ED severity (all p < 0.001). Profiles included a neurodivergent high-risk group, a cognitively compensated group, a sensory-reactive group, and a classically symptomatic group. Multinomial logistic regression predicted cluster membership with 94% accuracy. DISCUSSION: Neurodevelopmental dimensions meaningfully differentiate ED subgroups and may inform more personalized, stratified care. These findings highlight the importance of integrating autistic traits, sensory processing, and social cognition into ED assessment and treatment planning. PUBLIC SIGNIFICANCE STATEMENT: This study identifies four distinct neurodevelopmental and clinical profiles among women with eating disorders, defined by differences in autistic traits, sensory sensitivity, and social cognition. Understanding these profiles can help clinicians recognize the diversity of presentations in eating disorders and adapt interventions to the specific needs of each individual, particularly those with neurodivergent features, ultimately promoting more personalized and effective care.

Indexed as

Autism Spectrum DisorderFeeding and Eating DisordersSocial CognitionAdolescentAdultCluster AnalysisEmpathyFemaleHumansSurveys and QuestionnairesYoung Adultcluster analysiseating disordersneurodiversitypersonalized interventionsensory sensitivitysocial cognitionautistic traits

Identifiers

PMID40820436
PMCPMC12605647

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.