Evidence map›Paper›PMID 40820542›Full record

ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2025

The Inner Nuclear Membrane Has a Unique Lipid Signature.

Yang Niu, Tamas Balla

Abstract readReview
In one paragraph

Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. The Inner Nuclear Membrane Has a Unique Lipid Signature.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yang NiuInternational Center for Aging and Cancer, Hainan Medical University, Haikou, Hainan, China.ORCID https://orcid.org/0009-0008-9445-6266
Tamas BallaSection on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

Funding

Hainan Medical UniversityInternational Center for Aging and CancerIntramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health of the United States
6 · The paper itself

Abstract

Although the inner nuclear membrane (INM) is generally considered to be continuous with the outer nuclear membrane (ONM) and connected to the remaining endoplasmic reticulum (ER), it has been well recognized that it is functionally distinct, having a unique protein composition. It has increasingly been recognized, however, that the INM also differs from the ONM and the other ER domains in its lipid composition. It is an intriguing proposition that the unique lipid profile of the INM is intricately linked to its specialized functions related to the nuclear events. Despite rapid progress in recent years in our understanding of the unique lipid profile of the INM and its role in the control of nuclear functions, there is a lot that remains to be understood. This review summarizes recent advances in characterizing the INM lipid composition and lipid synthetic pathways including their possible roles in the control of nuclear functions. Additionally, it discusses current challenges and areas deserving further investigation.

Indexed as

Lipid MetabolismLipidsMembrane LipidsNuclear EnvelopeAnimalsCell NucleusEndoplasmic ReticulumHumansLipidsMembrane Lipidsdiacylglycerolinner nuclear membrane (INM)lipid profilesphosphatidic acidphosphatidylserine

Identifiers

PMID40820542
PMCPMC12455280

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.