Evidence map›Paper›PMID 40822873›Full record

ReviewF1000Research2025

Heavy Metal Contamination: Sources, Health Impacts, and Sustainable Mitigation Strategies with Insights from Nigerian Case Studies.

Babafemi Laoye, Peter Olagbemide, Tolulope Ogunnusi, Oghenerobor Akpor

Abstract readReview
In one paragraph

Review in F1000Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Babafemi LaoyeDepartment of Biological Sciences, Afe Babalola University, Afe Babalola University, Ado-Ekiti, Ekiti, 360101, Nigeria.ORCID https://orcid.org/0000-0003-0903-754X
Peter OlagbemideDepartment of Biological Sciences, Afe Babalola University, Afe Babalola University, Ado-Ekiti, Ekiti, 360101, Nigeria.ORCID https://orcid.org/0000-0003-4127-8132
Tolulope OgunnusiDepartment of Biological Sciences, Afe Babalola University, Afe Babalola University, Ado-Ekiti, Ekiti, 360101, Nigeria.
Oghenerobor AkporDepartment of Biological Sciences, Afe Babalola University, Afe Babalola University, Ado-Ekiti, Ekiti, 360101, Nigeria.ORCID https://orcid.org/0000-0002-4256-1549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heavy metal contamination has gradually become a highly significant global issue due to its continual existence in the environment and bioaccumulation in the ecosystems, posing deleterious risks to human health. The major objectives of the review is to investigate the sources, pathways, and toxicological impacts of heavy metals such as cadmium, lead, mercury, and arsenic, elucidating their health consequences and plausible mitigation strategies. Furthermore, the review explores the dual origins of heavy metal contamination; natural geological processes and anthropogenic activities such as industrial emissions, mining, and agricultural practices. These heavy metals seep into soil, water, and food chains, leading to bioaccumulation, bio-magnification and causing significant health risks, including cardiovascular diseases, neurological disorders, and reproductive toxicity. Additionally, the addition of indigenous case studies from Nigeria, such as lead poisoning in Zamfara State and contamination in the Great Kwa River of Cross Rivers State underscores the disproportionate impact of heavy metal pollution in developing nations. The key findings from this review via the selected case studies revealed the socio-economic and environmental dimensions of the issue, providing a contextual understanding of region-specific vulnerabilities and health outcomes. To address these problems, the review evaluates already existing mitigation strategies, including chelation therapy and phytoremediation, while proposing sustainable, cost-effective solutions for reducing exposure and mitigating impacts. It emphasizes the importance of integrative approaches involving policy, community engagement, and technological innovations to fight heavy metal contamination effectively. In conclusion, this review contributes to the understanding of heavy metal toxicity, giving and showcasing very much important insights into the sources and health implications of contamination. By integrating theoretical perspectives with practical solutions, this review provides a robust framework for informing policy makers and advancing sustainable environmental management practices.

Indexed as

Environmental PollutantsEnvironmental PollutionMetals, HeavyHumansNigeriaEnvironmental PollutantsMetals, HeavyHeavy metal; Phytoremediation; DNA; Cadmium; Lead; Arsenic; Mecury Anthropogenic; Bioaccumulation; Bio-magnification.

Identifiers

PMID40822873
PMCPMC12355173

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.