SynthesisFrontiers in oncology2025
A bibliometric analysis of inflammation and thyroid carcinoma: research trends and future perspectives.
Synthesis in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy and association with lymph node metastasis of the systemic immune-inflammation index in thyroid cancer: a systematic review and meta-analysis.Frontiers in immunology · 2026Pooled it
- Prognostic Value of Endoplasmic Reticulum Stress-Related Gene Signature in Thyroid Cancer.Current medical science · 2026Article
- DUSP6 promotes motility, invasion, and tumorigenicity of thyroid cancer cells via IL8-induced neutrophil extracellular traps.Scientific reports · 2026Article
- Predictive value of systemic inflammatory response index for the occurrence and prognosis of lung metastases in papillary thyroid carcinoma.American journal of translational research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and objectives: Thyroid carcinoma, one of the most prevalent endocrine malignancies, has witnessed a gradual increase in incidence in recent years. Accumulating evidence has demonstrated that inflammation plays a pivotal role in the pathogenesis, progression, and prognosis of thyroid carcinoma, with a significant association between certain malignancies and chronic inflammatory processes. This study conducts a bibliometric analysis of literature on inflammation and thyroid carcinoma over 24 years, aiming to identify trends and research dynamics. The findings are expected to deepen understanding of thyroid carcinoma mechanisms and guide new therapeutic strategies. Methods: We used the advanced search function of the Web of Science Core Collection to systematically screen and curate articles on inflammation and thyroid carcinoma published between 2000 and 2024. Using Microsoft Excel 2019, we analyzed and visualized publication volume and growth trends. For co-occurrence and clustering analysis of countries, institutions, authors, journals, references, and keywords, we employed VOSviewer, CiteSpace, and the 'bibliometrix' package in R. Keyword visualization identified 10 major clusters, including sodium iodide symporter, total thyroidectomy, peroxisome proliferator-activated receptor, papillary thyroid microcarcinoma, therapeutic radiopharmaceuticals, zoological gardens, endoscopic thyroidectomy, mixed cryoglobulinemia, fine needle aspiration, and clinical evaluation. The most frequent keywords were cancer, thyroid cancer, and inflammation. Results: We included a total of 1,441 articles published between 2000 and 2024, contributed by 8,326 authors from 2,054 institutions across 70 countries. These articles were published in 625 journals, encompassing 59,808 references and 6,340 keywords. The publication output demonstrated a consistent upward trend over the study period. Among the contributing nations, China emerged as the most prolific country in terms of publication volume. The leading institution was the University of Pisa in Italy. The most productive author was Antonelli, Alessandro, and the leading journal was Conclusion: This bibliometric analysis shows that research on inflammation and thyroid carcinoma is a rapidly evolving field, marked by diverse themes and in-depth studies. Advances in technology and extensive research are expected to clarify how inflammation drives thyroid carcinoma initiation and progression. This deeper understanding will lead to new approaches in diagnosis, prevention, and treatment of thyroid carcinoma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.