Evidence map›Paper›PMID 40823251›Full record

ArticleFrontiers in public health2025

Impact of visceral adiposity index on cognitive impairment and cognitive trajectories in Chinese middle-aged and older adults.

Siran Chen, Mengqi Zhou, Lin Han, Rui Ma, Xiaoyue Jiang, Ziyi Yang, Yuling Du, Yanfang Yang

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siran ChenDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Mengqi ZhouDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Lin HanDepartment of Neurology, West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Rui MaDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Xiaoyue JiangDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Ziyi YangDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Yuling DuDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Yanfang YangDepartment of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The association between the visceral adiposity index (VAI) and cognitive function in middle-aged and older Chinese adults is not well understood. The "obesity paradox"-where obesity appears to be linked with better health outcomes-has also been observed. This study aims to clarify the association by using data from a nationally representative longitudinal survey. Methods: This study analyzed five waves of data from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2020. The Cox proportional hazards regression model was used to assess the effect of VAI on the occurrence of cognitive impairment. Additionally, cognitive trajectories over the study period were identified using group-based trajectory modeling (GBTM), and the association between VAI and cognitive trajectories was further analyzed through multinomial logistic regression. Results: A total of 5,637 participants aged ≥45 years were included, of whom 46.6% were women. The risk of cognitive impairment was lower in participants with higher VAI scores (Q3: HR = 0.79, 95% CI: 0.67-0.94; Q4: HR = 0.83, 95% CI: 0.70-0.98). Cognitive trajectories over the 9-year period were categorized into four groups based on cognitive Z-scores: "high and stable" ( Conclusion: Greater visceral adiposity was associated with a lower risk of developing cognitive impairment and a more favorable cognitive trajectory over time.

Indexed as

Cognitive DysfunctionIntra-Abdominal FatObesity, AbdominalAgedChinaEast Asian PeopleFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk FactorsCHARLScognitive functioncognitive trajectoryvisceral adiposity indexvisceral obesity

Identifiers

PMID40823251
PMCPMC12354607

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.