Evidence map›Paper›PMID 40823948›Full record

SynthesisJournal of research in health sciences2025

Effect of Interventions on Iron-Deficiency Anemia Among School-Going Children in India: A Systematic Review and Network Meta-Analysis.

Flemin Felix, Kalesh Mappilakudy Karun, Chandan Nagendraswamy, Deepthy Melepurakkal Sadanandan, Yadu Damodaran, Manish Barvaliya, Subarna Roy

Abstract readNetwork Meta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of research in health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Flemin FelixDepartment of Health Systems Research, ICMR - National Institute of Traditional Medicine, Nehru Nagar, Belagavi, 590010, Karnataka, India.ORCID 0009-0009-5980-8681
Kalesh Mappilakudy KarunDepartment of Health Systems Research, ICMR - National Institute of Traditional Medicine, Nehru Nagar, Belagavi, 590010, Karnataka, India.ORCID 0000-0002-9940-8764
Chandan NagendraswamyDepartment of Health Systems Research, ICMR - National Institute of Traditional Medicine, Nehru Nagar, Belagavi, 590010, Karnataka, India.
Deepthy Melepurakkal SadanandanWomen's and Children's Health Research Unit, Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belagavi, 590010, Karnataka, India.
Yadu DamodaranDepartment of Biostatistics, St. Thomas College, Palai, 686574, Kerala, India.
Manish BarvaliyaDepartment of Health Systems Research, ICMR - National Institute of Traditional Medicine, Nehru Nagar, Belagavi, 590010, Karnataka, India.
Subarna RoyDepartment of Health Systems Research, ICMR - National Institute of Traditional Medicine, Nehru Nagar, Belagavi, 590010, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of iron-deficiency anemia (IDA) among school-aged children in India varies from 27% to 90%. There is no evidence of the comparative effects of various available interventions. Thus, this study aimed to quantify and rank the effects of different interventions on IDA among school-going children.

methodsTo this end, PubMed, Scopus, and ScienceDirect databases were searched, and randomized controlled trials (RCTs) evaluating the comparative effects of various interventions on hemoglobin (Hb) and serum ferritin against a control were included in this study. The random-effect model was conducted for Hb, and the fixed-effects model was performed for ferritin to estimate the mean difference (MD) and 95% confidence interval (CI) of the effect of interventions of outcomes based on the heterogeneity (I

resultsEight RCTs (including 2534 participants) investigating the effects of 12 interventions for IDA treatment among school-going children in India were obtained. The results of reference-based forest plots and

conclusionIt seems that iron-rich fish powder and intermittent IFA supplementation were the most effective interventions, but further research is needed to confirm these results and assess their public health implications.

Indexed as

Anemia, Iron-DeficiencyDietary SupplementsIronChildFerritinsHemoglobinsHumansIndiaRandomized Controlled Trials as TopicFerritinsHemoglobinsIronAnemiaHaemoglobinIndiaNetwork meta-analysisSchool-going childrenSystematic review

Identifiers

PMID40823948
PMCPMC12445883

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.