Evidence map›Paper›PMID 40824330›Full record

ReviewCurrent nutrition reports2025

Bio-Functionalities of Sesame (Sesamum indicum L.) Seed Meal and Proteins: Illuminating Their Novel Role and Mechanisms as Versatile Functional Food Ingredients for Health Promotion.

Fredrick Nwude Eze, Rattana Muangrat, Wachira Jirarattanarangsri, Thanyaporn Siriwoharn, Yongyut Chalermchat

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current nutrition reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fredrick Nwude EzeOffice of Research Administration, Chiang Mai University, Chiang Mai, 50200, Thailand. fredrickeze10@gmail.com.ORCID https://orcid.org/0000-0002-3742-9965
Rattana MuangratFaculty of Agro-Industry, Chiang Mai University, Chiang Mai, 50100, Thailand. rattanamuangrat@yahoo.com.ORCID https://orcid.org/0000-0002-7371-750X
Wachira JirarattanarangsriFaculty of Agro-Industry, Chiang Mai University, Chiang Mai, 50100, Thailand.ORCID https://orcid.org/0000-0001-6059-024X
Thanyaporn SiriwoharnFaculty of Agro-Industry, Chiang Mai University, Chiang Mai, 50100, Thailand.
Yongyut ChalermchatFaculty of Agro-Industry, Chiang Mai University, Chiang Mai, 50100, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of the reviewSesame seed meal (SSM), the by-product from sesame oil production, contains high amounts of bioactive compounds such as lignans, dietary fiber, and proteins. Increasing demand for functional foods and nutraceuticals for health enhancement has inspired an upturn in research exploring novel sources of natural, safe, and effective bioactive components. This is an up-to-date and comprehensive review of SSM, focusing on the role of its proteins/peptides in modulating physiological processes in the light of potential health improvement. RECENT

findingsMounting evidence from in vitro, in vivo and some clinical studies, suggest that SSM proteins and bioactive peptides interacted with, and effectively modulated vital molecular targets, metabolism, and physiological processes central to the pathogenesis of some chronic ailments. These include nuclear factor erythroid 2-related factor 2 pathway activation, regulation of renin-angiotensin-aldosterone system and metabolic enzymes, inhibition of aberrant protein aggregation, boosting antioxidant status, countering oxidative stress, modulating blood lipid levels, etc., resulting in anti-diabetic, anti-obesity, anti-hyperlipidemia, and neuroprotective effects. Consumption of SSM and its bioactive proteins/peptides can enhance the physiological processes vital for health and well-being, and perhaps counter the molecular perturbations underlying the development of chronic diseases. SSM proteins and biopeptides are highly promising bioactive ingredients that can be use in the development of functional foods and nutraceuticals aimed at health improvement in humans.

Indexed as

Functional FoodHealth PromotionPlant ProteinsSeedsSesamumAnimalsAntioxidantsBioactive Peptides, DietaryHumansOxidative StressAntioxidantsBioactive Peptides, DietaryPlant ProteinsBioactive peptidesChronic diseaseFunctional foodsNutraceuticalsOxidative stressSesame seed meal

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.