Evidence map›Paper›PMID 40826280›Full record

ArticleNpj viruses2025

Survival and transmission fitness of SARS-CoV-2 over the time-of-flight in an aerosolization chamber.

Yiying Zhang, Justin M Donovan, Dylan W Weninger, Victor Lam, Richard Gibson, Steven Renaud, Daniel Paquette, Alex Lescanec, Cody Hird, Christopher T DeGroot and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Npj viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yiying ZhangDepartment of Microbiology and Immunology, University of Western Ontario, 1151 Richmond St, London, ON, N6A 3K7, Canada.
Justin M DonovanDepartment of Pathology and Laboratory Medicine, University of Western Ontario, London, ON, Canada.
Dylan W WeningerDepartment of Microbiology and Immunology, University of Western Ontario, 1151 Richmond St, London, ON, N6A 3K7, Canada.
Victor LamDepartment of Microbiology and Immunology, University of Western Ontario, 1151 Richmond St, London, ON, N6A 3K7, Canada.
Richard GibsonDepartment of Microbiology and Immunology, University of Western Ontario, 1151 Richmond St, London, ON, N6A 3K7, Canada.
Steven RenaudCenterLine (Windsor) Limited, Windsor, ON, Canada.
Daniel PaquetteCenterLine (Windsor) Limited, Windsor, ON, Canada.
Alex LescanecCenterLine (Windsor) Limited, Windsor, ON, Canada.
Cody HirdDepartment of Pathology and Laboratory Medicine, University of Western Ontario, London, ON, Canada.
Christopher T DeGrootDepartment of Mechanical and Materials Engineering, University of Western Ontario, London, ON, Canada.
Jessica L ProdgerDepartment of Microbiology and Immunology, University of Western Ontario, 1151 Richmond St, London, ON, N6A 3K7, Canada.
Franco BerrutiDepartment of Chemical and Biochemical Engineering, University of Western Ontario, London, ON, Canada.
Eric SavoryDepartment of Mechanical and Materials Engineering, University of Western Ontario, London, ON, Canada.
Eric J ArtsDepartment of Microbiology and Immunology, University of Western Ontario, 1151 Richmond St, London, ON, N6A 3K7, Canada. earts@uwo.ca.

Funding

CIHR 165802
6 · The paper itself

Abstract

The impact of various environmental factors on SARS-CoV-2 transmission remains debated, partly due to limited physical experiments with infectious virus that closely replicate real-world conditions. Using a novel, self-contained containment level 3 chamber, we aerosolized the virus in different environmental conditions then collected droplets on nasal tissue, cell lines, or different materials to measure the transmission of infectious SARS-CoV-2. We found that SARS-CoV-2 survival was much shorter than previously reported for the potential of fomite transmission. Temperature, relative humidity and the presence of incinerated tobacco, cannabis, or vape products had no discernible impact on SARS-CoV-2 transmission through aerosolized droplets, but affected the survival of VSV, a non-respiratory enveloped virus. When compared to USA-WA1/2020 and the Omicron variant, Delta SARS-CoV-2 had the greatest survival during aerosolization. These findings suggest that respiratory enveloped viruses like SARS-CoV-2 may have and may be continuing to evolve higher transmission fitness through droplets.

Identifiers

PMID40826280
PMCPMC12361559

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.