Evidence map›Paper›PMID 40827252›Full record

ArticleRespirology case reports2025

Post-Engraftment Syndrome Following Autologous Haematopoietic Stem Cell Transplantation in a Patient With Relapsed Hodgkin Lymphoma.

Bader J Alghamdi, Maha A Safhi, Reuof M Almakati

Abstract read
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bader J AlghamdiCollege of Medicine King Saud Bin Abdulaziz University for Health Sciences Jeddah Saudi Arabia.
Maha A SafhiDepartment of Medicine, Faculty of Medicine King Abdulaziz University Jeddah Saudi Arabia.ORCID https://orcid.org/0000-0002-0895-383X
Reuof M AlmakatiCollege of Medicine King Saud Bin Abdulaziz University for Health Sciences Jeddah Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-engraftment syndrome (PES) is a significant and potentially life-threatening complication of autologous haematopoietic stem cell transplantation (AHSCT) that presents with fever, skin rash and pulmonary involvement. Despite its clinical relevance, PES remains a diagnostic challenge and is often misidentified as an infectious process, leading to a delay in the appropriate treatment. We report the case of a 38-year-old man with relapsed Hodgkin's lymphoma and glucose-6-phosphate dehydrogenase (G6PD) deficiency who developed severe PES following AHSCT. The patient experienced severe respiratory distress and an altered mental status, necessitating intubation and intensive care unit admission. Despite broad-spectrum antimicrobial coverage, his condition deteriorated until intravenous corticosteroids were administered, with a subsequent remarkable clinical response. This case highlights the importance of the early recognition and appropriate management of PES.

Indexed as

engraftment syndromehaematopoietic stem cell transplantationlymphomarespiratory distress syndrome

Identifiers

PMID40827252
PMCPMC12358217

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.