Evidence map›Paper›PMID 40828322›Full record

SynthesisEuropean journal of nutrition2025

Does a combined intervention of diet and exercise lead to a more positive impact on neurocognitive function? A systematic review and meta-analysis.

Chuan Qiu Shui Wang, Shi Yi Dong, Kun Wang, Yi Yang, Shi Qi Liu, Jiong Luo

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Optimal type and dose of exercise to improve cognitive function in healthy and pre-sarcopenic older adults: a bayesian network meta-analysis of randomized controlled trials.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chuan Qiu Shui WangSchool of Physical Education, Sports Rehabilitation Center, Southwest University, Chongqing, China.
Shi Yi DongSchool of Physical Education, Sports Rehabilitation Center, Southwest University, Chongqing, China.
Kun WangSchool of Physical Education, Sports Rehabilitation Center, Southwest University, Chongqing, China.
Yi YangSchool of Physical Education, Sports Rehabilitation Center, Southwest University, Chongqing, China.
Shi Qi LiuSchool of Physical Education, Sports Rehabilitation Center, Southwest University, Chongqing, China.
Jiong LuoSchool of Physical Education, Sports Rehabilitation Center, Southwest University, Chongqing, China. 784682301@qq.com.ORCID http://orcid.org/0009-0006-2158-5804

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have shown that lifestyle modifications, including diet and exercise, can help prevent cognitive decline. However, there are currently no comprehensive systematic reviews of the combined effects of diet and exercise on cognitive function.

methodsA systematic review of the literature identified randomized controlled trials that examined the effects of combined diet and exercise interventions on neurocognitive function compared with either intervention alone. The following databases were searched: PubMed, Web of Science, Embase, and Google Scholar. The search was conducted up until October 13, 2024. A meta-analysis was conducted using a random-effects model, and the quality of the evidence was evaluated using the GRADE approach.

resultsA total of 11 randomized controlled trials were subjected to analysis, comprising a total of 3428 participants. The combined diet and exercise intervention was found to significantly improve global cognitive function scores (SMD = 0.32, 95% CI 0.15 to 0.49, I

conclusionThe combined strategy of diet and exercise positively affects neurocognitive function, including overall cognitive function, memory, and executive function. However, no significant differences were found between the effects of combined interventions and single interventions on overall cognitive function.

Indexed as

CognitionCognitive DysfunctionDietExerciseExecutive FunctionFemaleHumansMaleRandomized Controlled Trials as TopicCognitive functionCombination therapyDiet therapyExecutive functionMemory functionPhysical exercise

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.