Evidence map›Paper›PMID 40828583›Full record

SynthesisWorld journal of surgery2025

New-Onset Diabetes Mellitus Following Pancreatic Injury: A Systematic Review.

V P C van Zon, M C Tol, P Krijnen, V A L Huurman, D A Ruess, I B Schipper

Abstract readSystematic Review
In one paragraph

Synthesis in World journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

V P C van ZonDepartment of Trauma Surgery, Leiden University Medical Center, Leiden, the Netherlands.ORCID https://orcid.org/0009-0005-9633-3807
M C TolDepartment of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.ORCID https://orcid.org/0000-0001-7064-2947
P KrijnenDepartment of Trauma Surgery, Leiden University Medical Center, Leiden, the Netherlands.
V A L HuurmanDepartment of Transplant Surgery, Leiden University Medical Center, Leiden, the Netherlands.
D A RuessDepartment of General and Visceral Surgery, Center for Surgery, Medical Center University of Freiburg, Freiburg, Germany.
I B SchipperDepartment of Trauma Surgery, Leiden University Medical Center, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPancreatic trauma is rare, accounting for only 0.2% of all trauma cases, and reports on long-term endocrine outcomes are scarce. Patients who undergo pancreatic resection may develop diabetes mellitus.

objectivesTo summarize the available literature reporting the incidence of diabetes mellitus (DM) after pancreatic trauma and to evaluate potential influences on the incidence rates. PATIENTS AND

methodsWe searched in PubMed and Embase for studies published between 1990 and July 2025 that enrolled patients with trauma of the pancreas and reported data on new-onset DM.

resultsOut of 906 identified records, six studies with a total of 297 patients with pancreatic trauma. The overall cumulative incidence of new-onset DM is 5.7% (95% confidence interval [CI]: 3.4%-9.0%). DM developed in 8.2% (95% CI: 4.4%-13.6%) of patients who underwent (partial) pancreatic resection and in 2.9% (95% CI: 0.8%-7.4%) of patients treated nonoperatively. For low-grade injuries, the incidence of DM was 5.5% (95% CI: 2.0%-11.5%) compared to 11.1% (95% CI: 4.9%-20.7%) for high-grade injuries. The time until new-onset diabetes mellitus was detailed in one study with 15 patients.

conclusionBased on the available literature, the estimated overall incidence of DM after pancreatic trauma is 5.7%. High-grade pancreatic injury seems to increase the risk of developing new-onset DM, which is possibly influenced by their frequent surgical treatment.

Indexed as

Diabetes MellitusPancreasHumansIncidencePancreatectomydiabetes mellitusendocrine dysfunctionpancreatic injurytrauma

Identifiers

PMID40828583
PMCPMC12515025

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.