Evidence map›Paper›PMID 40829368›Full record

ArticleJACC. Advances2025

Greenspace and Survival Among Older Women With Breast Cancer: Regional Variations Within the U.S. SEER-Medicare-Linked Database.

Jean C Bikomeye, Emily L McGinley, Yuhong Zhou, Sergey Tarima, Jamila L Kwarteng, Andreas M Beyer, Tina W F Yen, Aaron N Winn, Kirsten M M Beyer

Abstract read
In one paragraph

Article in JACC. Advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jean C BikomeyeMedical College of Wisconsin, Milwaukee, Wisconsin, USA. Electronic address: jbikomeye@mcw.edu.
Emily L McGinleyMedical College of Wisconsin, Milwaukee, Wisconsin, USA.
Yuhong ZhouMedical College of Wisconsin, Milwaukee, Wisconsin, USA.
Sergey TarimaMedical College of Wisconsin, Milwaukee, Wisconsin, USA.
Jamila L KwartengMedical College of Wisconsin, Milwaukee, Wisconsin, USA.
Andreas M BeyerMedical College of Wisconsin, Milwaukee, Wisconsin, USA.
Tina W F YenMedical College of Wisconsin, Milwaukee, Wisconsin, USA.
Aaron N WinnUniversity of Illinois at Chicago, Rockford, Illinois, USA.
Kirsten M M BeyerMedical College of Wisconsin, Milwaukee, Wisconsin, USA.

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
NCATS NIH HHS UL1 TR001436NCCDPHP CDC HHS U58 DP003862NCI NIH HHS HHSN261201000034CNCI NIH HHS HHSN261201000035CNCI NIH HHS HHSN261201000035INCI NIH HHS HHSN261201000140C
6 · The paper itself

Abstract

backgroundBreast cancer (BC) is the most frequently diagnosed cancer among women in the United States. Cardiovascular disease (CVD) is a major noncancer cause of death among BC survivors. Although greenspace is linked to better CVD and BC-related outcomes, its effect on BC survival is unknown.

objectivesThis study investigates the association between urban greenspace and survival among older BC survivors in the United States and examines regional differences.

methodsData from the 2010 to 2017 Surveillance, Epidemiology, and End Results-Medicare BC cohort was used. Women aged 66+ with invasive BC, enrolled in Medicare (Parts A and B) for 12 months prediagnosis and with known tract-level greenspace data (N = 86,300) were included. Greenspace was measured as census tract percent tree canopy quartiles. Survival outcomes included all-cause mortality (ACM), BC-specific mortality (BCSM), and CVD-specific mortality (CVDSM), with censoring by December 31, 2018. Covariates included age, comorbidity, race/ethnicity, Medicaid eligibility, tumor stage and subtype, neighborhood social vulnerability, and population density.

resultsOf 86,300 women, 22,541 (26.1%) died during the follow-up, 9,012 (40.6%) and 4,195 (18.9%) died from BC and CVD, respectively. Greater percent tree canopy was associated with lower ACM (HR: 0.90; 95% CI: 0.86-0.95) and BCSM (cause-specific HR: 0.90; 95% CI: 0.82-0.98). Regional variations were observed, with greenspace linked to lower ACM in California, New Jersey, and Michigan, and lower BCSM and CVDSM in California and New Jersey. Washington, Louisiana, and Georgia showed nonsignificant or inconsistent results.

conclusionsThis study highlights the importance of investigating the relationship between greenspace and cardiooncology-related outcomes across regions, underscoring the need for more place-specific research to guide targeted interventions to improve survival outcomes.

Indexed as

breast cancercardiovascular diseasessurvivalurban greenspace

Identifiers

PMID40829368
PMCPMC12396096

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.