Evidence mapPaperPMID 40830299Full record

ReviewArchives of pharmacal research2025

Enhancer regulation in cancer: from epigenetics to m

Arathy Vasukutty, Poshan Yugal Bhattarai, Hong Seok Choi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of pharmacal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Arathy VasukuttyCollege of Pharmacy, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju, 61452, Republic of Korea.ORCID http://orcid.org/0000-0003-4616-2374
Poshan Yugal BhattaraiCollege of Pharmacy, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju, 61452, Republic of Korea.ORCID http://orcid.org/0000-0001-9388-966X
Hong Seok ChoiCollege of Pharmacy, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju, 61452, Republic of Korea. chs@chosun.ac.kr.ORCID http://orcid.org/0000-0001-7862-2342

Funding

Chosun University 2024
6 · The paper itself

Abstract

Enhancers are crucial cis-regulatory DNA elements that regulate gene transcription by interacting with promoters, often over long genomic distances. Unlike promoters, their activity is independent of orientation or proximity to the gene. Active enhancers are transcribed into non-coding enhancer RNAs (eRNAs), which help stabilize enhancer-promoter loops, recruit transcription machinery, and shape the chromatin architecture. These eRNAs are regulated post-transcriptionally, through modifications such as the N6-methyladenosine (m

Indexed as

AdenosineEnhancer Elements, GeneticEpigenesis, GeneticNeoplasmsRNA, UntranslatedAnimalsGene Expression Regulation, NeoplasticHumansRNA MethylationAdenosineN-methyladenosineRNA, UntranslatedCancer therapyEnhancer RNAEnhancersEnhancer targetingSuper-enhancers

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.