Evidence map›Paper›PMID 40830616›Full record

ArticleScientific reports2025

Reduced IFN-γ-expressing SARS-CoV-2 specific CD4

Rona Kartika, Dicky Levenus Tahapary, Farid Kurniawan, Syahidatul Wafa, Tika Pradnjaparamita, Simon P Jochems, Heri Wibowo, Imam Subekti

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rona KartikaDoctoral Program in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, 10430, Indonesia.
Dicky Levenus TahaparyMetabolic Disorder, Cardiovascular, and Aging Research Center,, Indonesia Medical Education & Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia.
Farid KurniawanMetabolic Disorder, Cardiovascular, and Aging Research Center,, Indonesia Medical Education & Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia.
Syahidatul WafaMetabolic Disorder, Cardiovascular, and Aging Research Center,, Indonesia Medical Education & Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia.
Tika PradnjaparamitaMetabolic Disorder, Cardiovascular, and Aging Research Center,, Indonesia Medical Education & Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia.
Simon P JochemsLeiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center (LUMC), Albinusdreef 2, Leiden, 2333, Netherlands.
Heri WibowoMetabolic Disorder, Cardiovascular, and Aging Research Center,, Indonesia Medical Education & Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia. bowoheri04@gmail.com.
Imam SubektiDivision of Endocrinology, Metabolism, and Diabetes, Department of Internal Medicine, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jl. P. Diponegoro No. 71, Jakarta, 10430, Indonesia. imam.subekti@ui.ac.id.

Funding

Universitas Indonesia NKB-377/UN2.RST/HKP.05.00/2023
6 · The paper itself

Abstract

Insulin resistance is one of the metabolic complications of COVID-19. Our previous study showed a 22% median increase in homeostasis model assessment-estimated insulin resistance (HOMA-IR) in obese individuals at 12 months post-infection compared to acute infection. This study aimed to investigate the association between various subsets of IFN-γ-expressing SARS-CoV-2-specific CD4

Indexed as

CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCOVID-19Insulin ResistanceInterferon-gammaObesitySARS-CoV-2AdultAgedCase-Control StudiesFemaleHumansLymphocyte ActivationMaleMiddle AgedInterferon-gammaCOVID-19ExhaustionInsulin resistanceSenescentT cells

Identifiers

PMID40830616
PMCPMC12365270

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.