Evidence map›Paper›PMID 40831167›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2025

[Clinical and immunological features for early differentiation between primary immune thrombocytopenia and connective tissue disease in children].

Fu-Rong Kang, Mei Yan, Ying-Bin Yue, Hailiguli Nuriddin, Yong-Feng Cheng, Yu Liu

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Fu-Rong KangPediatric Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Mei YanPediatric Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Ying-Bin YuePediatric Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Hailiguli NuriddinPediatric Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Yong-Feng ChengPediatric Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Yu LiuPediatric Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the clinical and immunological features of children with primary immune thrombocytopenia (pITP) or connective tissue disease (CTD) with thrombocytopenia as the initial manifestation at initial diagnosis, and to provide a basis for early differentiation.

methodsA retrospective study was performed on 236 children with pITP (pITP group) or CTD with thrombocytopenia as the initial manifestation (CTD-TP group) who were admitted from January 2019 to August 2024. Clinical and immunological indicators were compared between the two groups to identify potential influencing factors for early differentiation and their discriminative validity.

resultsCompared with the pITP group, the CTD-TP group had a significantly older age of onset and significantly lower leukocyte count, eosinophil count, lymphocyte count, and complement C4 level (

conclusionsThere is heterogeneity in the clinical and immunological indicators between children with pITP and CTD-TP at initial diagnosis, and these research findings can help with the early differentiation between the two diseases.

Indexed as

Connective Tissue DiseasesPurpura, Thrombocytopenic, IdiopathicAdolescentAge of OnsetBiomarkersChildChild, PreschoolComplement C4C-Reactive ProteinDiagnosis, DifferentialEarly DiagnosisFemaleHumansImmunoglobulin EImmunoglobulin MInfantBiomarkersComplement C4C-Reactive ProteinImmunoglobulin EImmunoglobulin MChildConnective tissue diseasePrimary immune thrombocytopeniaThrombocytopenia

Identifiers

PMID40831167
PMCPMC12369532

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.