Evidence map›Paper›PMID 40831801›Full record

ArticleExperimental and therapeutic medicine2025

Correlation of telomere length between full and preterm neonates and their mothers.

Elena Vakonaki, Maria Theodora Vitiadou, Nefeli Ioanna Paraskevopoulou, Manolis Tzatzarakis, Stella Baliou, Petros Ioannou, Athanasios Alegakis, Thomas Lamprakis, Persefoni Fragkiadaki, Eleftheria Mylonaki and 7 more

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Placental Pathophysiology and Developmental Programming of Adult Cardiometabolic Risk: A Narrative Review of Pregnancy Exposures.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Elena VakonakiLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Maria Theodora VitiadouLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Nefeli Ioanna ParaskevopoulouLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Manolis TzatzarakisLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Stella BaliouLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Petros IoannouDepartment of Internal Medicine and Infectious Diseases, University Hospital of Heraklion, 71110 Heraklion, Greece.
Athanasios AlegakisLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Thomas LamprakisLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Persefoni FragkiadakiLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Eleftheria MylonakiDepartment of Neonatology and Neonatal Intensive Care Unit, University Hospital of Heraklion, 71500 Heraklion, Greece.
Zoi VolonakiDepartment of Obstetrics and Gynecology, University Hospital of Heraklion, 71500 Heraklion, Greece.
Nicolina AnagnostatouDepartment of Neonatology and Neonatal Intensive Care Unit, University Hospital of Heraklion, 71500 Heraklion, Greece.
Fanourios MakrygiannakisDepartment of Obstetrics and Gynecology, University Hospital of Heraklion, 71500 Heraklion, Greece.
Antonios MakrigiannakisDepartment of Obstetrics and Gynecology, University Hospital of Heraklion, 71500 Heraklion, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece.
Aristides TsatsakisLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Eleftheria HatzidakiDepartment of Neonatology and Neonatal Intensive Care Unit, University Hospital of Heraklion, 71500 Heraklion, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telomeres are nucleoprotein complexes that serve as protective caps from the DNA damage response at the ends of chromosomes. During aging, telomeres gradually shorten, and genomic instability arises through the induction of senescence. The present study aimed to elucidate the association between maternal characteristics, their medical history and pregnancy details with the telomere length (TL) of neonates. Blood samples were collected from 54 mothers and their neonates, and DNA extraction and measurement of TL was performed by quantitavive PCR. The results showed that maternal TL was negatively correlated with body mass index before pregnancy. A weak to moderate significant correlation was observed between maternal and neonatal TL. Non-significant differences were found between the maternal TL and their smoking habits, as well as medical and gestation history.

Indexed as

pre and full-term neonatespregnancyquantitave PCRtelomere length

Identifiers

PMID40831801
PMCPMC12360152

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.