Evidence map›Paper›PMID 40831934›Full record

ArticleFrontiers in oncology2025

Metastatic colon adenocarcinoma to the gingiva treated with spatial fractionation radiotherapy: a case report.

Xinyi Liu, Ke Xu, Quan Yao, Jian Fang, Weiyi Zhou, Jinyi Lang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinyi LiuDepartment of Radiation Oncology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Ke XuDepartment of Radiation Oncology, Radiation Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Quan YaoDepartment of Radiation Oncology, Radiation Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Jian FangDepartment of Radiation Oncology, Radiation Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Weiyi ZhouDepartment of Radiation Oncology, Radiation Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Jinyi LangDepartment of Radiation Oncology, Radiation Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastatic colon adenocarcinoma to the gingiva is exceedingly rare, accounting for 1-3% of maxillofacial malignancies and usually associated with advanced disease and poor prognosis. This case report describes a 68-year-old woman diagnosed with metastatic colon adenocarcinoma presenting with a metastatic lesion measuring 5 × 3 cm located in the left maxilla. The patient received hybrid spatial fractionation radiotherapy (SFRT) combining stereotactic body radiotherapy (SBRT) with conventional SFRT protocols. Post-radiotherapy, the lesion regressed significantly, bleeding ceased, and oral function improved. However, the patient passed away less than two months after the radiotherapy, due to the high systemic tumor burden and severe disease progression. This case highlights SFRT's efficacy in local symptom control for rare gingival metastases, despite systemic progression. This report underscores the need for optimized SFRT protocols and multidisciplinary approaches in managing metastatic colorectal cancer.

Indexed as

colonic neoplasmsgingival metastasisneoplasm metastasisradiotherapyspatially fractionated radiation therapy

Identifiers

PMID40831934
PMCPMC12358431

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.