ArticleFrontiers in public health2025
Respiratory pathogens in infants and young children with acute respiratory illness: a prospective cohort study, China, 2023-2024.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Protecting Newborns from Multidrug-Resistant Infections: The Emerging Role of Bacteriophages.Viruses · 2026Review
- Caregiver awareness of pediatric respiratory red-flag signs and emergency activation intentions: a province-wide cross-sectional study in China.Frontiers in medicine · 2026Article
- Impact of PCV13 Vaccination on Pharyngeal Detection ofChina CDC weekly · 2025Article
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Infants are vulnerable to acute respiratory infections (ARIs), which result in pediatric morbidity and even fatalities. A surge of ARIs among infants and young children was reported in China in 2023, garnering global attention. We aimed to investigate the frequency and types of respiratory pathogens associated with the risk of acute respiratory illnesses in infants and young children during this period. Methods: We established a cohort of 2-month-old healthy infants across three counties in Suqian City, Jiangsu Province, China. The infants in the cohort donated throat swabs at enrollment and then underwent a follow-up for active monitoring of common ARIs. Throat swabs collected from infants experiencing common ARIs were analyzed for respiratory pathogens using targeted next-generation sequencing (tNGS). Results: Between 7 February and 17 April 2023, a total of 804 infants were invited to participate. Among them, 796 participants were enrolled (423 [53.1%] male, 373 [46.9%] female) with a median age of 71.0 days. Frequently detected respiratory pathogen carriers at baseline included Conclusion: Our data provide a better understanding of epidemiological patterns of respiratory pathogens in infants and young children from 2023 to 2024. CMV,
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