Evidence map›Paper›PMID 40832017›Full record

ArticleFrontiers in public health2025

Respiratory pathogens in infants and young children with acute respiratory illness: a prospective cohort study, China, 2023-2024.

Yuqing Li, Mingwei Wei, Lunbiao Cui, Xiang Huo, Lisha Ma, Ran Tao, Tao Wu, Suyang Qi, Baolong Wang, Xiuyun Shi and 9 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yuqing Li *School of Public Health, National Vaccine Innovation Platform, Nanjing Medical University, Nanjing, China.
Mingwei Wei *School of Public Health, National Vaccine Innovation Platform, Nanjing Medical University, Nanjing, China.
Lunbiao Cui *Jiangsu Provincial Medical Innovation Center, National Health Commission Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing, China.
Xiang Huo *Jiangsu Provincial Medical Innovation Center, National Health Commission Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing, China.
Lisha MaSchool of Public Health, Southeast University, Nanjing, China.
Ran TaoJiangsu Provincial Medical Innovation Center, National Health Commission Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing, China.
Tao WuJiangsu Provincial Medical Innovation Center, National Health Commission Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing, China.
Suyang QiSucheng District Center for Disease Control and Prevention, Suqian, China.
Baolong WangSuyu District Center for Disease Control and Prevention, Suqian, China.
Xiuyun ShiSiyang County Center for Disease Control and Prevention, Suqian, China.
Yuanbao LiuJiangsu Provincial Medical Innovation Center, National Health Commission Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing, China.
Wenqing LiuSchool of Public Health, National Vaccine Innovation Platform, Nanjing Medical University, Nanjing, China.
Yiyue GeJiangsu Provincial Medical Innovation Center, National Health Commission Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing, China.
Li ChenSiyang County Center for Disease Control and Prevention, Suqian, China.
Xiujuan ZhaoSuyu District Center for Disease Control and Prevention, Suqian, China.
Jingjing WuSucheng District Center for Disease Control and Prevention, Suqian, China.
Runjie QiSchool of Public Health, National Vaccine Innovation Platform, Nanjing Medical University, Nanjing, China.
Fengcai ZhuSchool of Public Health, National Vaccine Innovation Platform, Nanjing Medical University, Nanjing, China.
Jingxin LiSchool of Public Health, National Vaccine Innovation Platform, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infants are vulnerable to acute respiratory infections (ARIs), which result in pediatric morbidity and even fatalities. A surge of ARIs among infants and young children was reported in China in 2023, garnering global attention. We aimed to investigate the frequency and types of respiratory pathogens associated with the risk of acute respiratory illnesses in infants and young children during this period. Methods: We established a cohort of 2-month-old healthy infants across three counties in Suqian City, Jiangsu Province, China. The infants in the cohort donated throat swabs at enrollment and then underwent a follow-up for active monitoring of common ARIs. Throat swabs collected from infants experiencing common ARIs were analyzed for respiratory pathogens using targeted next-generation sequencing (tNGS). Results: Between 7 February and 17 April 2023, a total of 804 infants were invited to participate. Among them, 796 participants were enrolled (423 [53.1%] male, 373 [46.9%] female) with a median age of 71.0 days. Frequently detected respiratory pathogen carriers at baseline included Conclusion: Our data provide a better understanding of epidemiological patterns of respiratory pathogens in infants and young children from 2023 to 2024. CMV,

Indexed as

Respiratory Tract InfectionsAcute DiseaseChinaFemaleHumansInfantMaleProspective Studiesacute respiratory infectionscohort studyinfants and young childrenpathogenstargeted next-generation sequencing

Identifiers

PMID40832017
PMCPMC12358494

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.