ArticleMethods in molecular biology (Clifton, N.J.)2025
Micropost Arrays to Model ECM Fiber Obstacles During Cell Migration in Confinement.
Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Micropost arrays are a valuable platform for studying cell migration in controlled microenvironments. These arrays enable researchers to mimic how migrating cells deform their nuclei in reaction to physical constraints presented by extracellular matrix (ECM) fibers during processes such as wound healing and cancer metastasis. By tuning micropost patterns and sizes, researchers can not only explore the impact of confining spaces created by such patterns on cell migration, signaling, and nuclear deformation but also simultaneously quantify cell-generated forces and forces of nuclear deformation. This paper outlines methods to design and fabricate ECM fiber mimicking micropost arrays for use in fundamental studies of confining cell migration.
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