ReviewProbiotics and antimicrobial proteins2026
Antimicrobial Peptides as Next-Generation Disinfectants: Tackling Biocide and Antimicrobial Resistance in Hospital Hygiene - A Narrative Review.
Review in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- A macrophage-mimetic nanocarrier co-loaded with geraniol and FK13-a1 for MRSA-induced acute lung injury.Drug delivery · 2026Article
- Protecting Newborns from Multidrug-Resistant Infections: The Emerging Role of Bacteriophages.Viruses · 2026Review
- Antimicrobial Resistance in Cancer Care: Challenge and Path Forward.Health science reports · 2026Review
- Thermo-Responsive Smart Hydrogels: Molecular Engineering, Dynamic Cross-Linking Strategies, and Therapeutics Applications.Gels (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global burden of antimicrobial resistance (AMR) and healthcare-associated infections (HAIs) is exacerbated by an increase in the number of biocide-resistant pathogens in hospital settings. Traditional disinfection methods face limitations, such as biofilm resilience, environmental hazards, and inadvertent selection of resistant strains. This review explores peptide-based disinfectants as innovative solutions to these challenges and highlights their broad-spectrum antimicrobial activity, biodegradability, and eco-friendliness. Antimicrobial peptides (AMPs) exhibit mechanisms such as membrane disruption, biofilm inhibition, and bridging the gap between conventional and probiotic disinfectants. Innovations in peptide design and bioengineering have enhanced their efficacy against multidrug-resistant pathogens, including vancomycin-resistant Staphylococcus aureus and carbapenem-resistant Enterobacteriaceae (CRE). AMP-based solutions have shown a 70-90% reduction in pathogen load in hospital trials, surpassing traditional disinfectants in terms of both effectiveness and safety. This review also emphasizes the feasibility of AMP-based disinfectants in resource-limited settings, where AMR and biocide resistance are particularly problematic. By analyzing the challenges, innovations, and economic aspects of integrating peptide-based disinfectants into hospital hygiene protocols, this study underscores their transformative potential. AMP-based solutions offer sustainable alternatives to combat AMR and biocide resistance, paving the way for more effective global infection-control strategies.
Indexed as
Identifiers
40833722What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.