Evidence map›Paper›PMID 40833797›Full record

ArticleMicrobial genomics2025

Freshwater snail faecal metagenomes reveal environmental reservoirs of antimicrobial resistance genes across two continents.

Angus M O'Ferrall, Alexandra Juhász, Sam Jones, Peter Makaula, Gladys Namacha, Shaali Ame, David Oguttu, Aidan Foo, Sekeleghe A Kayuni, E James LaCourse and 3 more

Abstract read
In one paragraph

Article in Microbial genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Angus M O'FerrallDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.
Alexandra JuhászDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.
Sam JonesDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.
Peter MakaulaMalawi Liverpool Wellcome Programme, Queen Elizabeth Central Hospital, Blantyre, Malawi.
Gladys NamachaMalawi Liverpool Wellcome Programme, Queen Elizabeth Central Hospital, Blantyre, Malawi.
Shaali AmeNeglected Tropical Diseases Program, Ministry of Health, Stone Town, Zanzibar, Tanzania.
David OguttuVector Control Division, Ministry of Health, Kampala, Uganda.
Aidan FooDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.
Sekeleghe A KayuniDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.
E James LaCourseDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.
Janelisa MusayaMalawi Liverpool Wellcome Programme, Queen Elizabeth Central Hospital, Blantyre, Malawi.
J Russell StothardDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.
Adam P RobertsDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

The transfer of antimicrobial resistance genes (ARGs) from environmental microbes to pathogens is a critical but underexplored One Health driver of antimicrobial resistance. Here, we evaluate freshwater snails, which are geographically widespread aquatic invertebrates, as environmental reservoirs of ARGs. We collected faeces from eight gastropod genera at 15 freshwater locations across Malawi, Uganda, Zanzibar and the UK and conducted the first freshwater snail faecal metagenomic study. We detected putative ARGs predicted to confer resistance to 13 antibiotic classes, including carbapenems. All ARGs that could be assembled into metagenome-assembled genomes (MAGs) were found within

Indexed as

Drug Resistance, MicrobialMetagenomeSnailsAnimalsFecesFresh WaterMalawiTanzaniaUgandaUnited Kingdomantimicrobial resistance (AMR)carbapenemasegastropodaMCROne HealthOXA-181

Identifiers

PMID40833797
PMCPMC12367435

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.